Nisin
Nisin is a natural polypeptide antibacterial substance produced by Streptococcus lactis. Its acute oral toxicity in rats is LD₅₀ > 2000 mg/kg body weight (belonging to the "actually non-toxic" level, with LD₅₀ > 500 mg/kg as a reference for low toxicity). Its toxicity level is close to that of table salt (LD₅₀ about 3000 mg/kg), and much lower than that of common food additives (such as sodium benzoate with LD₅₀ about 2700 mg/kg).
The intraperitoneal injection of LD₅₀ in mice was 700 mg/kg, and the intravenous injection of LD₅₀ was 325 mg/kg, both indicating an extremely low risk of acute toxicity.
In the 90-day feeding experiment of rats, when the dose reached 1000 mg/kg body weight per day, no abnormalities in indicators such as body weight, blood biochemistry, and histopathology were observed. Two-year carcinogenicity experiments have shown that even high-dose exposure does not induce tumorigenesis.
In 2018, the EFSA (European Food Safety Authority) of the European Union evaluated and determined that Nisin had no risk of genotoxicity, reproductive toxicity or chronic toxicity within the reasonable use range.
Other supplier products
|
|
Nisin in Beverages |
Application in Beverages: Controlling Heat-Resistant Spores and Microbial GrowthBeverages (e.g., fruit juices, beer, functional drinks) face risks ... |
|
|
Tilmicosin Premix 500g |
Tilmicosin premix is a veterinary medication that is used to treat and prevent respiratory infections in livestock. The medication is a broad-spect... |
|
|
Nisin as a natural antimicrobial peptide |
Nisin, a natural antimicrobial peptide produced by Lactococcus lactis, is widely used in food preservation and freshness retention due to its stron... |
|
|
Gentamycin Sulfate Soluble Powder |
Gentamycin Sulfate Soluble Powder is a type of antibiotic medication used to treat bacterial infections in animals. It is a broad-spectrum antibiot... |
|
|
Florfenicol Powder |
Product name: ShengxuelefengGeneric name: Florfenicol PowderActive ingredient: FlorfenicolDescription: Shengxuelefeng is a white or off-white powde... |
供应产品
Same products
