99% Local Anesthetic Powder Pharmaceutical Raw Material Lidocaine Base CAS 137-58-6

1.Basic Info.

Name:Lidocaine
CAS: 137-58-6
Assay: 99%
Appearance: White crystalline powder
Packing: 25kg/drum
EINECS: 205-302-8
Molecular Formula: C14H22N2O
Molecular weight: 234.34
Manufacturer: YUANCHENG
Usage: Topically used to relieve itching, burning and pain from skin inflammations, injected as a dental anesthetic, or as a local anesthetic for minor surgery.

Product Name	Lidocaine
Other Name	2-(Diethylamino)-N-(2,6-dimethylphenyl) acetamide
Assay (%)	≥99.5	Odor	Characteristic
Color	White crystalline powder	Cas No.	137-58-6
Molecular Formula	C14H22N2O	Molecular Weight	234.34
Standard	USP30
Function	Main functions are as follows: 1.Local anesthetic. 2. Treating Epilepsy. 3. Treating Asthma.
Applications	Main applications are as follows: Applied in pharmaceuticalfields.
Packing	1kgor 5kg/bag, 25kg/drum
Shelf Life	24 months
Storage	Store in sealed containers at cool & dry place. Protect from light, moisture and pest infestation.

2.Product Description:

Lidocaine, xylocaine, or lignocaine is a common local anesthetic and class-1b antiarrhythmic drug. Lidocaine is used topically to relieve itching, burning, and pain from skin inflammations, injected as a dental anesthetic, or as a local anesthetic for minor surgery.It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic healthcare system.
Lidocaine is the most important class-1b antiarrhythmic drug; it is used intravenously for the treatment of ventricular arrhythmias (for acute myocardial infarction, digoxin poisoning, cardioversion, or cardiac catheterization) if amiodarone is not available or contraindicated. Lidocaine should be given for this indication after defibrillation, CPR, and vasopressors have been initiated. A routine prophylactic administration is no longer recommended for acute cardiac infarction; the overall benefit of this measure is not convincing.



3.Product Applications:

The efficacy profile of lidocaine as a local anesthetic is characterized by a rapid onset of action and intermediate duration of efficacy. Therefore, lidocaine is suitable for infiltration, block, and surface anesthesia. Longer-acting substances such as bupivacaine are sometimes given preference for subdural and epidural anesthesias; lidocaine, though, has the advantage of a rapid onset of action.
Epinephrine vasoconstricts arteries, reducing bleeding and also delays the resorption of lidocaine, almost doubling the duration of anaesthesia. For surface anesthesia, several available formulations can be used e.g. for endoscopies, before intubations, etc. Buffering the pH of lidocaine makes local freezing less painful.[2] Lidocaine drops can be used on the eyes for short ophthalmic procedures.
Relative insensitivity to lidocaine is genetic. In hypokalemic sensory overstimulation, relative insensitivity to lidocaine has been described in people who also have attention deficit hyperactivity disorder.In dental anesthesia, a relative insensitivity to lidocaine can occur for anatomical reasons due to unexpected positions of nerves. Some people with Ehlers-Danlos syndrome are insensitive to lidocaine.
Lidocaine, along with ethanol, ammonia, and acetic acid, has also been proven to be effective in treating jellyfish stings, both numbing the affected area and preventing further nematocyst discharge
Lidocaine crosses the blood-brain and placental barriers, presumably by passive diffusion.
Lidocaine is metabolized rapidly by the liver, and metabolites and unchanged drug are excreted by the kidneys. Biotransformation includes oxidative N-dealkylation, ring hydroxylation, cleavage of the amide linkage, and conjugation. N-dealkylation, a major pathway of biotransformation, yields the metabolites monoethylglycinexylidide and glycinexylidide. The pharmacological/toxicological actions of these metabolites are similar to, but less potent than, those of Lidocaine. Approximately 90% of Lidocaine administered is excreted in the form of various metabolites, and less than 10% is excreted unchanged. The primary metabolite in urine is a conjugate of 4-hydroxy-2, 6-dimethylaniline.




4.COA

Items Tested Specification BP2007 Result Characters White or slightly yellow crystal powder with characteristic odor White crystal powder with weak odor Melting point Melting point: 66 degree to 70 degree 66.6 degree-68.5 degree Identification BCDE Comply with the requirement Conforms Appearance of solution Clear and colorless Conforms Water Not more than 0.5% 0.3% Sulphate Not more than0. 1% Conforms Chloride Not more than 0. 0035% 0.0025% Heavy Metals Not more than 0.002% 0.001% Residue on Ignition Not more than 0.1% 0.02% Impurity (26-dimethylaniline content) Not more than 0.01% Conforms Assay (HPLC) 99.0%-101.0% 99.6% Conclusion Conforms BP2007

5.Why choose us?

1.Good quality.All products are produced under GMP conditions according to Standard Operation Procedure(SOP), not from little underground labs or black markets, so the quality is guaranteed.

2.Discreet packing methods.For your safety and to insure delivery all products will be packed in adiscreet way to prevent any suspicions, no steroids related name will appear on the parcels.

3.99.99% customs clearance rate.We have rich experience in shipping parcel to USA, Australia, UK, Canada, Brazil, Russia, Germany, Poland, Mexico, etc.

4.Injectable steroid.We offer melting powder into liquid service.And ship the liquid in special bottles.




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7.Order Guide

Q1:Have your Product Quality been Approved by Third Party Lab?
A:Yes, All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc.So you will be assured with Good Quality if you choose us.

Q2:How do you treat quality complaint?
A:First of all, our QC department will do strict examination of our export products by HPLC, UV, GC,
TLC and so on in order to reduce the quality problem to near zero.If there is areal quality problem, caused by us, we will send you free goods for replacement or refund your loss.

Q3:Is there any discount?
A:Yes, for larger quantity, we always support with better price.

Q4:How long does it take to the goods arrived?
A:It is Depending on your location,
For small order, please expect 5-7 days by DHL, UPS, TNT, FedEx, EMS.
For mass order, please allow 5-8 days by Air, 20-35 days by Sea.

Q5 Do you have any reshipment policy?
We have good after-sale service and re-shipment policy if the parcel lose
Our long association with our clients has brought great benefits
We always take the upmost care in the packaging of our products
Our clients will confirm this as even they struggle to find them without help at times.
But in spite of our best efforts it is still possible will seize asmall number of packages.
In this circumstance we promise reship free to establish long term relationship

Q6:Can Iget asample?
A:Of course.For most products we can provide you afree sample, while the shipping cost should
Undertake by your side.

We are aleading manufacturer of steroid raw materials, .And Peptides
Many distributors and labs, bodybuilders from worldwide cooperate with us,
All speak highly of our safe shipping and goods.
If you require further information please donot hesitate to contact us.



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