Fumarate Vonoprazan, TAK-438
CAS No.1260141 27 2 Fumarate Vonoprazan
Vonoprazan fumarate fda approval (TAK-438), a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB), with antisecretory activity. Vonoprazan Fumarate inhibits H+, K+-ATPase activity in porcine gastric microsomes with an IC50 of 19 nM at pH 6.5. Vonoprazan Fumarate is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease.
Synonym
Vonaprazan; 5-(2-Fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl)-1H-pyrrole-3-methanamine2-butenedioate(Vonoprazan); 1-[5-(2-fluorophenyl)-1-pyridin-3-Chemicalbookylsulfonylpyrrol-3-yl]-N-methylmethanamine; AK-438; Vonaprazan(TAK-438); vonoprazan(tak-438); Vonoprazanfumarate(TAK-438); vonoprazan(tak
CAS No.:
EC No.: 250-635-4
MF: C21H20FN3O6S
MW: 461.46
Parameters of Fumarate Vonoprazan, TAK-438
Item Specification Results
Appearance Off-white To White Crystalline Powder White Crystalline Powder
Solubility Soluble In Dmso, Slightly Soluble In Methanol, Water, Very Slightly Soluble In Alcohol. Complies
Identification 1HNMR Complies
Melting Point 196-201℃ 198-199℃
Residue On Ignition NMT0.2% 0.03%
Water NMT0.5% 0.12%
Single Impurity NMT0.1% 0.034%
Total Impurities NMT0.5% 0.121%
Heavy Metals NMT20PPM Complies
Assay 99.0-101.0% 99.69%
Packing:
100g/bag; 500g/bag; 1kg/bag; 25kg/drum
Recommended storage method:
Store in a cool, dry and ventilated place.
Recommended storage temperature:
2 - 8 °C
Product usage:
Antigastric drugs
As one of bulk chemical suppliers, we will do our best to meet all the needs of customers.
We can also offer kinds of powder supplements for sale, more details, please visit our website.
Other supplier products
|
|
Cistanche Tubulosa Extract (Verbascoside 9%min) |
Cistanche cistanche is parasitic on the roots of tamarisk, and its main producing area is Hetian, Xinjiang. After being dried, it is very hard and ... |
|
|
Fucoidan |
Fucoidan Fucoidans belong to a class of complex sugar molecules known as a polysaccharides. All fucoidans share the same backbone structure, but va... |
|
|
Oclacitinib Maleate |
Oclacitinib Maleate
Oclacitinib Maleateis a useful pet care product for dogs at least 1 year of age as an oral pet dog. Oclacitinib maleate for do... |
|
|
Glutathione Powder Bulk |
Glutathione Bulk Pure glutathione powder is an antioxidant, a molecule that helps fight free radicals. Free radicals are unstable molecules that fo... |
|
|
Palmitoylethanolamide Powder (CAS 544-31-0) |
What Is Palmidrol?
Palmitoylethanolamide Powder (CAS 544-31-0)
Our factory has been producing Palmitoylethanolamide powderfor many years. As the ... |
All supplier products
Same products
