Fumarate Vonoprazan, TAK-438
CAS No.1260141 27 2 Fumarate Vonoprazan
Vonoprazan fumarate fda approval (TAK-438), a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB), with antisecretory activity. Vonoprazan Fumarate inhibits H+, K+-ATPase activity in porcine gastric microsomes with an IC50 of 19 nM at pH 6.5. Vonoprazan Fumarate is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease.
Synonym
Vonaprazan; 5-(2-Fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl)-1H-pyrrole-3-methanamine2-butenedioate(Vonoprazan); 1-[5-(2-fluorophenyl)-1-pyridin-3-Chemicalbookylsulfonylpyrrol-3-yl]-N-methylmethanamine; AK-438; Vonaprazan(TAK-438); vonoprazan(tak-438); Vonoprazanfumarate(TAK-438); vonoprazan(tak
CAS No.:
EC No.: 250-635-4
MF: C21H20FN3O6S
MW: 461.46
Parameters of Fumarate Vonoprazan, TAK-438
Item Specification Results
Appearance Off-white To White Crystalline Powder White Crystalline Powder
Solubility Soluble In Dmso, Slightly Soluble In Methanol, Water, Very Slightly Soluble In Alcohol. Complies
Identification 1HNMR Complies
Melting Point 196-201℃ 198-199℃
Residue On Ignition NMT0.2% 0.03%
Water NMT0.5% 0.12%
Single Impurity NMT0.1% 0.034%
Total Impurities NMT0.5% 0.121%
Heavy Metals NMT20PPM Complies
Assay 99.0-101.0% 99.69%
Packing:
100g/bag; 500g/bag; 1kg/bag; 25kg/drum
Recommended storage method:
Store in a cool, dry and ventilated place.
Recommended storage temperature:
2 - 8 °C
Product usage:
Antigastric drugs
As one of bulk chemical suppliers, we will do our best to meet all the needs of customers.
We can also offer kinds of powder supplements for sale, more details, please visit our website.
Other supplier products
|
|
Fish Collagen Peptide |
China Fish Collagen Peptide Factory Gihi Chemicals fish collagen protein powder adopts advanced directional bio-enzymatic hydrolysis technology and... |
|
|
Afoxolaner |
Afoxolaner for dogsis used to treat and control flea and tick infestations in dogs. After being ingested by a dog, afoxolaner is distributed throug... |
|
|
Cistanche Tubulosa Extract (Verbascoside 9%min) |
Cistanche cistanche is parasitic on the roots of tamarisk, and its main producing area is Hetian, Xinjiang. After being dried, it is very hard and ... |
|
|
GHK Copper Peptide Powder |
The tripeptide-1 (glycyl-L-histadyl-L-lysine or GHK) is primarily known as carrier peptides. It mainly helps to stabilize and deliver copper. It is... |
|
|
CAS 111 60 4 Ethylene Glycol Monostearate, 2-Hydroxyethyl Stearate |
Ethylene glycol mono stearate, more commonly known as glycol monostearate or glycol stearate, is an organic compound. It is the ester of ethylene g... |
供应产品
Same products
