Copolymers(VP/VA)
Copolymers(VP/VA)
Copovidone Manufacturer for VP/VA64 Pharmaceutical Excipient Supply
Yuking supplies Copovidone, also known as VP/VA64, PVP/VA 64 or Vinylpyrrolidone Vinyl Acetate Copolymer, for pharmaceutical formulation development and commercial excipient supply.
As a Copovidone manufacturer and VP/VA64 supplier, Yuking provides PVP/VA 64 for direct compression, dry granulation, wet granulation, film coating, solid dispersion and hot melt extrusion formulation projects. This product category is suitable for pharmaceutical manufacturers, CDMOs, tablet producers and excipient distributors that require a reliable water-soluble copolymer binder with technical documentation support.
- Product Name: Copovidone / VP/VA64 / PVP/VA 64
- Chemical Type: Vinylpyrrolidone-vinyl acetate copolymer
- Main Function: Dry binder, tablet binder, film former and solid-dispersion polymer
- Application: Direct compression, dry granulation, wet granulation, film coating and HME formulation development
- Documents: TDS, SDS, COA and product specification support upon request
Request Copovidone VP/VA64 TDS, COA or Quotation
Copovidone VP/VA64 for Pharmaceutical Formulations
Copovidone VP/VA64 is a water-soluble copolymer of N-vinyl-2-pyrrolidone and vinyl acetate. It is used as a pharmaceutical excipient when a formulation requires dry binding, wet binding, film-forming performance or polymer-matrix supportin oral solid dosage forms.
Compared with Povidone homopolymer, PVP/VA 64 provides a different balance of hydrophilicity, binding performance and film-forming behavior because of the vinyl acetate component. This makes Copovidone VP/VA64 suitable for tablets, granules, coatings and poorly soluble API development projects.
Why Choose Yuking Copovidone VP/VA64?
Yuking Copovidone VP/VA64 is supplied for pharmaceutical projects that require a functional water-soluble copolymer binder and supporting technical documents. The product can be evaluated in multiple oral solid dosage processes, including direct compression, dry granulation, wet granulation and film coating.
- Dry binder support for direct compression tablet formulations;
- Polymer binder support for dry granulation and roller compaction;
- Water-soluble binder support for wet granulation;
- Film-forming polymer for tablet coating and subcoating systems;
- Polymer matrix option for solid dispersion and hot melt extrusion development;
- Technical information support for tablet hardness, compactability and formulation stability evaluation;
- TDS, SDS, COA and product specification support for formulation review and supplier qualification.
Main Applications of Copovidone VP/VA64
Direct Compression Binder
Copovidone VP/VA64 can be evaluated as a direct compression binder for tablet formulations. In direct compression, a suitable dry binder supports tablet strength, compactability and compression performance without adding a wet granulation step.
For direct compression projects, Yuking can provide product information for formulation review, including specification data, COA, SDS and technical documentation according to project requirements.
Dry Granulation and Roller Compaction
PVP/VA 64 can be used in dry granulation or roller compaction processes where water or solvent introduction needs to be reduced. This is relevant for moisture-sensitive formulations and processes designed to simplify oral solid dosage manufacturing.
Copovidone VP/VA64 can support granule strength, tablet compactability and process development in suitable dry granulation systems.
Wet Granulation Binder
Copovidone can also be evaluated as a water-soluble binder for wet granulation. It supports granule formation and tablet integrity in oral solid dosage forms.
Yuking supplies Copovidone VP/VA64 for formulation teams working with binder solutions, granulation processes, drying conditions and scale-up evaluation.
Film Coating and Subcoating
Copovidone VP/VA64 has film-forming properties and can be evaluated in tablet coating, subcoating and barrier-layer systems. It can support coating adhesion, film integrity and formulation flexibility depending on the coating system.
For film coating applications, the product may be reviewed together with plasticizers, solvents, pigments and other coating excipients according to the finished dosage form requirements.
Solid Dispersion and Hot Melt Extrusion
PVP/VA64 can be considered as a polymer matrix for solid dispersion and hot melt extrusion development, especially in projects involving poorly soluble APIs.
In solid dispersion and HME development, Copovidone VP/VA64 may support polymer-matrix formation, dissolution performance evaluation and formulation stability studies.
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