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Hepcinat (Sofosbuvir 400mg)

Composition:Each film coated tablet contains: Sofosbuvir equivalent to Sofosbuvir 400 mg.
Sofosbuvir 400mg tabletsis an antiviral drug which is used in combination with other drugs for treatment of Hepatitis C Virus (HCV) infection. Compared to previous treatments, sofosbuvir based regimens provide a higher cure rate, fewer side effects, and a two- to four-fold reduced duration of therapy.

Mechanism of Action:-Sofosbuvircontains oral nucleotide analog inhibitor of the hepatitis C virus (HCV) polymerase. The drug is a direct-acting antiviral agent and interferes straight with the HCV lifecycle, restraining the viral replication. It can be incorporated into HCV RNA by the NS5B polymerase and acts as a chain terminator. The drug is available for oral use in the form of HEPCINAT 400mg tablets.

Dosage and Administration:The recommended daily dose of Sofosbuvir is 400 mg tablet to be taken once daily with or without food.Sofosbuvirshould be used in combination with Ribavirin or in combination with Pegylated Interferon and Ribavirin for the treatment of CHC (Chronic Hepatitis C) in adults. It is highly advisable to administer the drug under strict medical supervision and advice.

Side Effects:

Adverse events associated with the use of Sofosbuvir in combination with Ribavirin may include but are not limited to, the following

  • Fatigue
  • Headache

Adverse events associated with the use of Sofosbuvir in combination with Peginterferon Alfa and Ribavirin may include, but are not limited to, the following:

  • Fatigue
  • Headache
  • Nausea
  • Insomnia
  • Anemia

Packaging: Each Bottle contains 28 tablets of Sofosbuvir 400 mg.
Storage: Store at 25°C in a dry place.



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