Biological Activity of N-Acetyl-DL-Tryptophan
Biological Activity of N-Acetyl-DL-Tryptophan
1. Stable tryptophan supplementation activity
As a derivatized form of tryptophan, it can be slowly metabolized and decomposed in organisms to release DL-tryptophan, supplement essential amino acids, and participate in body protein synthesis and nitrogen balance regulation.
2. Antioxidant and anti-oxidative damage activity
It weakens the oxidative degradation of the indole ring through amino acetylation modification, exhibits stronger antioxidant capacity than ordinary tryptophan, scavenges free radicals, and reduces oxidative stress damage to cells and biological active substances.
3. Protein and biomacromolecule protective activity
It can stabilize the spatial structure of proteins and polypeptides, inhibit molecular aggregation, denaturation and hydrolysis, reduce the damage of external environmental factors to bioactive components, and maintain biological activity of biological preparations.
4. Regulation of neurotrophic metabolism
After in vivo hydrolysis, the released tryptophan acts as a precursor of serotonin and melatonin, participating in nervous system metabolism, regulating nerve excitation, and assisting in improving emotional balance and sleep-related physiological activities.
5. Metabolic regulation and anti-stress activity
It participates in intermediate metabolism of organisms, improves metabolic adaptability, enhances physiological anti-stress ability, and relieves metabolic disorders caused by external adverse factors in cells and organisms.
6. Low metabolic irritation and biocompatible activity
With mild properties and low biological irritation, it has good biocompatibility in vivo and in vitro, will not produce obvious toxic and side effects, and is suitable for long-term acting as a protective agent and nutritional substrate in pharmaceutical and biological systems.
7. Microbial growth-promoting activity
It can be utilized by microorganisms and cultured cells as a slow-release amino acid source, promoting the growth and reproduction of beneficial strains and normal cell proliferation, and optimizing the culture microenvironment.
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