Tacrolimus
Tacrolimus (also FK-506 or fujimycin, trade names Prograf, Advagraf, Protopic) is an immunosuppressive drug that is used mainly after allogeneic organ transplant to reduce the activity of the patient's immune system and so lower the risk of organ rejection. It is also used in a topical preparation in the treatment of atopic dermatitis (eczema), severe refractory uveitis after bone marrow transplants, exacerbations of minimal change disease, TH2 mediated diseases such as Kimura's disease and the skin condition vitiligo.
It is a 23-membered macrolide lactone discovered in 1984 from the fermentation broth of a Japanese soil sample that contained the bacteria Streptomyces tsukubaensis. It reduces interleukin-2 (IL-2) production by T-cells.
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Tacrolimus |
Tacrolimus (also FK-506 or fujimycin, trade names Prograf, Advagraf, Protopic) is an immunosuppressive drug that is used mainly after allogeneic or... |
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Varenicline |
Varenicline (trade name Chantix in the USA and Champix in Canada, Europe and other countries, marketed by Pfizer, usually in the form of vareniclin... |
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moxidectin |
Moxidectin (Milbemycin B[1]) kills parasites, so is used for the prevention and control of heartworm and intestinal worms, and can be found in trea... |
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Trilostane |
It was withdrawn from human use in the United States market in April 1994.[3][4] The drug is available in the United Kingdom for use in humans unde... |
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pimobendan |
Pimobendan (INN is a veterinary medication manufactured by Boehringer Ingelheim under the trade names Vetmedin and Acardi) or pimobendane. It is a ... |
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