H3K56ac
As one of the professional custom peptide synthesis companiesin China, KS-V Peptide has been specialized in providing customized peptides synthesisservices(including Toxins and Analogues, Ubiquitins and Ubiquitin Probes, Post-translational Histones and other peptide manufacturing, APIs and process optimization of the pharmaceutical peptide.
SPECIFICATION OF H3K56AC
|
CAT |
H3201 |
|
Product Name |
HistoneH3-K56ac |
|
Purity |
≥95% by HPLC analysis |
|
Appearance |
White powder |
|
Usage |
Research use only |
|
Storage |
Shipping at room temperature. Upon delivery aliquot. Stored at -20°C or -80°C. Avoid freeze/thaw cycle. |
|
Sequence |
ARTKQTARKS TGGKAPRKQL ATKAARKSAP ATGGVKKPHR YRPGTVALRE IRRYQK(ac)STEL LIRKLPFQRL VREIAQDFKT DLRFQSSAVM ALQEACEAYL VGLFEDTNLC AIHAKRVTIM PKDIQLARRI RGERA |
APPLICATION OF H3K56AC
H3K56acis a covalent modification known as a mark of newly replicated chromatin as well as replication-independent histone replacement. H3K56ac is important for chromatin remodeling and serves as a marker of new nucleosomes during DNA replication but its role in the cell cycle is debated. Lysine 56 is located at the amino-terminal αN-helix and close to the site where the DNA enters and exits the nucleosome. Due to its location on the lateral surface of the nucleosome, which is close to the DNA entry/exit site and interacts with DNA. The studies on yeast might not apply to mammals. Mammalian cells do not express HATs with high specificity to K56. Sirtuins can catalyze the removal of the acetyl group from K56. H3K56ac levels are elevated in cancer and pluripotent cells. TRIM66 reads unmodified H3R2K4 and H3K56ac to respond to DNA damage.
在线联系供应商
Other supplier products
 |
PSALMOTOXIN 1 | ASIC1a channels, Psalmotoxin-1 inhibits cation currents mediated by acid-sensing ion channels (ASIC1a)1,2 SPECIFICATION OF PSALMOTOXIN 1 ... |
 |
L CARNOSINE | LCarnosineis a dipeptide (sequence: beta-Ala-His) and a well-documented water-borne antioxidant with wound healing activity, and naturally occurs i... |
|
|
H3K56ac | As one of the professional custom peptide synthesis companiesin China, KS-V Peptide has been specialized in providing customized peptides synthesis... |
 |
CALCICLUDINE | L-type Ca2+ channels. Calcicludineis a potent and specific antagonist of neuronal L-type CaV channels1. SPECIFICATION OF CALCICLUDINE Product Nam... |
 |
H3S10PH | Synthesized histone H3 peptide corresponding to residues within 1-135 of human histone H3 with phosphorylation S10 modification. SPECIFICATION O... |
Same products
 |
PakGent CL-F025P T25 Cell Culture Flask | 卖方: PakGent Bioscience (Suzhou) Co., Ltd. | PS, 25cm², TC treated. With a generous 25 cm² surface area, these T25 cell culture fla... |
 |
PakGent Cryogenic Boxes | 卖方: PakGent Bioscience (Suzhou) Co., Ltd. | Cryogenic boxes are special temperature-controlled storage containers used to store and transport... |
 |
PakGent STSS-509CG clear plastic tubes with end caps | 卖方: PakGent Bioscience (Suzhou) Co., Ltd. | Self standing, with O-ring, clear tube with green cap. The PakGent STSS-509CG clear plastic tube... |
 |
PakGent NMPB500A Brown Plastic Medicine Bottles | 卖方: PakGent Bioscience (Suzhou) Co., Ltd. | 500ml packaging bottle, amber. PakGent NMPB500A Brown Plastic Medicine Bottlesoffer secure sto... |
 |
PakGent PT-5000B-T Thermo Scientific Art Tips | 卖方: PakGent Bioscience (Suzhou) Co., Ltd. | Thermo pipette, clear, bulk pack. PakGent PT-5000B-T Thermo Scientific Art Tips offer precisio... |
