HPMC E5
KimaCell®Hypromellose E5is pharma grade hydroxypropyl methyl cellulose, pharmaceutical excipients play an important role in the development and production of formulations. For example, in sustained-release preparations, polymer materials such as cellulose ether are used as pharmaceutical excipients in sustained-release pellets, various matrix sustained-release preparations, coated sustained-release preparations, sustained-release capsules, sustained-release drug films, and resin drug sustained-release preparations. Preparations and liquid sustained-release preparations have been widely used. In this system, polymers such as cellulose ether are generally used as drug carriers to control the release rate of drugs in the human body, that is, it is required to release slowly in the body at a set rate within a certain time range to achieve the purpose of effective treatment.
Specification of HPMC E5
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HPMC E5 |
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Hydroxypropyl Methyl Cellulose (HPMC) |
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Physical Analysis |
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Appearance |
White to slightly off-white fibrous or granular powder. |
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Identification A to E |
Conform |
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Solution appearance |
Conform |
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Methoxy |
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Hydroxypropoxy |
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Loss on drying |
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Residue on ignition |
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pH |
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Apparent viscosity |
4-6cps |
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Particle size |
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Heavy Metals |
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Heavy Metal |
≤10ppm |
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Arsenic |
≤3ppm |
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Lead |
≤3ppm |
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Mercury |
≤1ppm |
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Cadmium |
≤1ppm |
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Micro bacteria |
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Total plate count |
≤1000cfu/g |
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Yeast and Mould |
≤100cfu/g |
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Coli form |
Absent/g |
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Salmonella |
Absent/g |
HPMC E5 Uses
KimaCell® hydroxypropyl methylcellulose e5are basically in the middle and high-end fields of the pharma industry, with high added value. Due to strict quality requirements, the production of pharmaceutical-grade cellulose ether is also relatively difficult. It can be said that the quality of pharmaceutical grade hydroxypropyl methylcellulose products can basically represent the technical strength of cellulose ether enterprises. Cellulose ether is usually added as a blocker, matrix material and thickener to make sustained-release matrix tablets, gastric-soluble coating materials, sustained-release microcapsule coating materials, sustained-release drug film materials, etc.
Natural cellulose ether is a general term for a series of cellulose derivatives produced by the reaction of alkali cellulose and etherifying agent under certain conditions. It is a product in which the hydroxyl groups on cellulose macromolecules are partially or completely replaced by ether groups.
If you want to find a reliable cellulose ether factory, please contact us, and we will be your best partner.
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