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Pharmaceutical Raw Materials Respiratory System Drugs Roflumilast for COPD

Pharmaceutical Raw Materials Respiratory System Drugs Roflumilast for COPD Basic Info. Roflumilast Synonyms: ROFLUMILAST;3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide;B 9302-107;BY 217;BYK 20869;Daxas;Roflumilast / 3-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide;3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide CAS: MF: C17H14Cl2F2N2O3 MW: 403.21 MP: 158°C storage temp. Refrigerator Chemical Properties Crystallin Solid Usage Selective phosphodiesterase 4(PDE4) inhibitor. Antiasthmatic; in treatment of chronic obstructive pulmonary disease Purity: 99% Usage: API Package: 1KG foil bag; 25Kg drum Description: Roflumilast is a phosphodiesterase-4 (PDE-4) inhibitor. Due to its selective inhibition of the PDE4 isoenzyme in lung cells, roflumilast is indicated for the management of chronic obstrtuctive pulmonary disease (COPD) exacerbations. Treatment with Roflumilast is associated with an increase in psychiatric adverse reactions, including suicide and suicidal attempts.



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