DMG-PEG2000
DMG-PEG2000
DMG-PEG 2000 is a synthetic lipid formed by the PEGylation of myristoyl diglyceride. It is used to manufacture lipid nanoparticles that are used in mRNA vaccines, and in particular forms part forms part of the drug delivery system for the Moderna COVID-19 vaccine. DMG-PEG2000 is also used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG2000 can help reduce antibody association (opsonization) by serum proteins and clearance by phagocytes thus conferring longer systemic circulation.
DMG-PEG (2000) is soluble in organic solvents such as ethanol and dimethyl formamide. The solubility of DMG-PEG (2000) in these solvents is approximately 1 mg/ml. DMG-PEG(2000) is also slightly soluble in DMSO.
SPECIFICATIONS OF DMG-PEG2000
Product name DMG-PEG2000
Chemical name 1,2-dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000
CAS No.
CDE Record registration Number F
FDA DMF Number 036553
Grade Injection
Quality standards manufacturer's standard
Molecular formula C32H62O5(C2H4O)n, n≈45
Content determination >95%
DMG PEG 2000 Molecular weight 2509.2
Product Code O02005
Available Package Sizes 1g
KEY BENEFITS OF DMG-PEG2000
PEG2000 DMG pharma has high purity; CDE/DMF registration;
Moderna COVID-19 vaccine
ADVANTAGES AND APPLICATIONS OF DMG-PEG2000
High purity; CDE/DMF registration; DMG-PEG 2000 is a synthetic lipid formed by the PEGylation of myristoyl diglyceride. DMG PEG 2000 is used to manufacture lnp lipid nanoparticle that are used in mRNA vaccines, and in particular forms part forms part of the drug delivery system for the Moderna COVID-19 vaccine.
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