DMG-PEG2000
DMG-PEG2000
DMG-PEG 2000 is a synthetic lipid formed by the PEGylation of myristoyl diglyceride. It is used to manufacture lipid nanoparticles that are used in mRNA vaccines, and in particular forms part forms part of the drug delivery system for the Moderna COVID-19 vaccine. DMG-PEG2000is also used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG2000 can help reduce antibody association (opsonization) by serum proteins and clearance by phagocytes thus conferring longer systemic circulation.
DMG-PEG (2000) is soluble in organic solvents such as ethanol and dimethyl formamide. The solubility of DMG-PEG (2000) in these solvents is approximately 1 mg/ml. DMG-PEG(2000) is also slightly soluble in DMSO.
SPECIFICATIONS OF DMG-PEG2000
|
Product name |
DMG-PEG2000 |
|
Chemical name |
1,2-dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000 |
|
CAS No. |
|
|
CDE Record registration Number |
F |
|
FDA DMF Number |
036553 |
|
Grade |
Injection |
|
Quality standards |
manufacturer's standard |
|
Molecular formula |
C32H62O5(C2H4O)n, n≈45 |
|
Content determination |
>95% |
|
DMG PEG 2000 Molecular weight |
|
|
Product Code |
O02005 |
|
Available Package Sizes |
1g |
KEY BENEFITS OF DMG-PEG2000
PEG2000 DMG pharma has high purity; CDE/DMF registration;
Moderna COVID-19 vaccine
ADVANTAGES AND APPLICATIONS OF DMG-PEG2000
High purity; CDE/DMF registration; DMG-PEG 2000 is a synthetic lipid formed by the PEGylation of myristoyl diglyceride. DMG PEG 2000 is used to manufacture lnp lipid nanoparticle that are used in mRNA vaccines, and in particular forms part forms part of the drug delivery system for the Moderna COVID-19 vaccine.
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