Preparative Liquid Chromatography System
Hanbon preparative liquid chromatography system has the characteristics of high efficiency, high speed, high automation, and explosion-proof, and is widely used in the separation and purification of pharmaceutical intermediates, biopharmaceuticals, synthetic drugs, natural products, fine chemicals, food additives and other fields. Including: CS-Prep® industrial preparative adsorption hplcsystem, Newstyle® laboratory liquid chromatography system, Intepure™ Integrated liquid chromatograph etc.
The Difference Between Analytical And Preparative Hplc System
Analytical chromatography, reflecting the composition of the sample, seeks efficient separation and high sensitivity without the need to collect specific fractions, and eluates are usually disposed of as waste liquids. In preparative process chromatography, however, the maximum amount of product must be produced in the minimum amount of time in order to save investment and operating costs. Due to the difference in purpose, there are major differences in the optimisation of the operating parameters chosen for preparative chromatography and analytical chromatography, including column size, packing, flow rate, operating pressure, injection volume, product purity, product recovery and chromatographic separation effectiveness. The former requires the smaller the injection volume, while the latter requires the column to be overloaded in order to increase the preparation volume. There are two types of column overloading, one is "mass overloading", where a smaller injection volume is maintained and the injection concentration is increased, and the other is "volume overloading", where a smaller injection concentration is maintained and the injection volume is increased. In preparative chromatography, mass overloading is generally considered to be preferable. In preparative chromatography separations, both separation and column efficiency decrease as the degree of mass overloading increases. However, operating with mass overload can increase the preparative volume provided that the separation can be achieved.
Preferred Options For Impurity Preparation
Impurity studies are carried out throughout the life cycle of pharmaceutical development. Impurity preparation is one of the bitter seas of sample purification, and the traditional approach is to use glass chromatography columns or analytical or semi-preparative HPLC to enrich bit by bit. The DAC50 with NS4210 chromatography system is 5-20 times more efficient than a 20 ml/min system with high throughput screening + excellent batch reproducibility. The system can also be equipped with an optional automatic fraction collector to increase automation and allow more focus on drug development.
For more informationabout hplc chromatography stepsand latest hplc instruments, please feel free to contact us!
在线联系供应商
Other supplier products
 |
MCC® Manual Chromatography Column | MCC® adopts the compression way by manual screw to load packing materials, with the advantages of concise configuration , easy for cleaning and ... |
 |
Continuous Ion Exchange Chromatography | Continuous dissociation technology is developed by combining the traditional fixed resin bed technology with the continuous counter-current system.... |
 |
Continuous Chromatographic System | Continuous chromatography systems By implementing this approach, the utilization rate of the ion exchange column can be enhanced, resulting in inc... |
 |
SFC-Dynamic Axial Compression Column | SFC-Dynamic Axial Compression Column (DAC) has the most mature loading technology in the field of preparative chromatography. It can self load, mai... |
 |
Bio-Pro® Pilot & Process Chromatography System | Bio-Pro® pilot&industrial chromatography systemsis suitable for pilot and large-scale production of biopharmaceutical purification processe... |
Same products
 |
MECHANIC MEC 4K 2K 高清电子目镜相机，适用于立体显微镜 | 卖方: 深圳市维客修科技有限公司 | 描述 美卡尼克MEC 2K/2K PRO/4K高清电子目镜摄像机，可以将双目立体显微镜改装成三目显微镜。采用SONY 1/2.3"进口CMOS传感器，采用优质CMOS传感器，硬... |
 |
Fluke 15B+ 17B+ 18B+ 数字万用表电压频率测试仪 | 卖方: 深圳市维客修科技有限公司 | iFixes 10CC半透明/全透明/乳白色/浅无铅助焊膏适用于手机主板CPU BGA维修。iFixes助焊剂注射器注射焊膏焊接膏手机整理焊接耗材系列，适用于电路板纳米芯片，手机PCB， SMT... |
 |
HTT-02 Hot Tack Tester | 卖方: Cell Instruments Co., Ltd | The HTT-02 Hot Tack Testeris specifically designed to assess this property by measuring the stren... |
 |
SPC-01 Stretch Film Peeling Cling Tester | 卖方: Cell Instruments Co., Ltd | The SPC-01 Stretch Film Peeling Cling Testermeasures the adhesion between two layers of stretch f... |
 |
FTT-01 Film Thickness Tester | 卖方: Cell Instruments Co., Ltd | The FTT-01 FilmThickness Testerutilizes a mechanical scanning technique to measure the thickness ... |
