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If you are going to consult the information about from one of the leading manufacturers and suppliers in China,Website:, Biopharmaleader Co.,Ltd is always at your service.Product InformationCAS NO. Product NameRibociclibSynonymsLEE011FormulaC23H30N8OMolecular Weight434.54Spec / Purity98%minSupply CapacityDetailsRibociclib (LEE011) is an orally available cyclin-dependent kinase (CDK) inhibitor targeting cyclin D1/CDK4 and cyclin D3/CDK6 cell cycle pathway, with potential antineoplastic activity. It specifically inhibits CDK4 and 6, thereby inhibiting retinoblastoma (Rb) protein phosphorylation. Inhibition of Rb phosphorylation prevents CDK-mediated G1-S phase transition, thereby arresting the cell cycle in the G1 phase, suppressing DNA synthesis and inhibiting cancer cell growth. Overexpression of CDK4/6, as seen in certain types of cancer, causes cell cycle deregulation.

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If you are going to consult the information about from one of the leading manufacturers and suppliers in China,Website:, Biopharmaleader Co.,Ltd ...
If you are going to consult the information about from one of the leading manufacturers and suppliers in China, Biopharmaleader Co.,Ltd is always...
If you are going to consult the information about from one of the leading manufacturers and suppliers in China, Biopharmaleader Co.,Ltd is always...
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