.

Contrast Media Manufacturing Company

For the purpose of medical imaging, a certain substance is introduced into the human body to change the image contrast of local tissues of the body. This introduced substance is Contrast Media, also known as Contrast Agents. As the first contrast media suppliersin China, Beilu Pharma, as one of the most professional contrast media companies, launched the domestic MRI Contrast Media Gadopentetate Dimeglumine Injection in 1992, which broke the foreign products monopoly and filled the domestic gap. As a well-known contrast media company, we could provide a broad portfolio stems Contrast Media across CT/X-ray and MRI modalities, and own the EU standard manufacturing facilities.

Types of Contrast Media in Beilu Pharma

MRI CONTRAST MEDIA

Magnetic Resonance Imaging (MRI)Contrast Media is Gadolinium based contrast agent(GBCA). It is an intravenous injection, mainly used to enhance the image quality of internal organs, blood vessels and tissues during MRI examinations. GBCA contains gadolinium, which is connected to each other through carrier molecules to form a chelating agent. According to the different chemical structures, this contrast medium can be divided into two categories: linear and macrocyclic. The linear structure of the imaging agents is easier to release gadolinium ions, and the macrocyclic structure of the contrast material is more stable and less likely to release gadolinium ions.

CT/X-RAY CONTRAST MEDIA

Iodine-containing Contrast Media is one of the common imaging contrast agents used in radiology diagnosis and interventional therapy. It is also a basic diagnosis drug for cardiovascular imaging under X-ray. Currently, the iodinated Contrast Media used for cardiovascular system CT and digital subtraction angiography are all water-soluble organic iodinated contrast materials.

Finished Types of Contrast Media

Product name

Characteristic

Specification

1

Gadopentetate Dimeglumine Injection

Injectable solution

469mg/ml: 10ml, 12ml, 15ml, 20ml

2

Gadobutrol Injection

Injectable solution

3

Ammonium iron citrate

Oral granules

3g:0.6g(Fe 129mg)

6g:1.2g(Fe 258mg)

4

Iopamidol Injection

Injectable solution

300mgI/ml: 50ml, 100ml

370mgI/ml: 50ml, 100ml

5

Iodixanol Injection

Injectable solution

270mgI/ml: 100ml

320mgI/ml: 50ml, 100ml

6

Iohexol Injection

Injectable solution

300mgI/ml: 20ml,50ml,75ml, 100ml

350mgI/ml: 20ml, 50ml, 100ml

API & Intermediates Types of Contrast Media

Products

CAS NO.

Packings

Classification

1

Iohexol

66108-95-0

25kg

Contrast agent

2

Iodixanol

92339-11-2

25kg

Contrast agent

3

Iopromide 

73334-07-3

25kg

Contrast agent

4

Iopamidol

60166-93-0

25kg

Contrast agent

5

Ioversol

87771-40-2

25kg

Contrast agent

6

Gadopentetate Monomeglumine

92923-57-4

25kg

Contrast agent

7

Gadopentetate Dimeglumine

86050-77-3

25kg

Contrast agent

8

Gadobutrol

25kg

Contrast agent

9

Calcobutrol

2kg

Excipients

10

Repaglinide

10kg

Anti-diabetic

11

Diethylenetriaminepentaacetic acid ( Pentaacetic Acid)(DTPA)

67-43-6

Intermediates

12

Iopamidol Intermediate (order based) 5-Amino-2,4,6-triiodoisophthalic acid

35453-19-1

25kg

Intermediates

Comparison of physicochemical characteristics of commonly used Contrast Media

Contrast media

(Concentration:mg(I)/ml)

Osmotic pressure

(mOsm/kg water)

Viscosity

(cP,37℃)

Iopamidol 300

616

Ioverol 300

651

Iohexol 300

672

Iobitridol 300

695

6

Iodixanol 320

290

The osmotic pressure of normal people is about 290-300mOsm/kg.

Taking the viscosity of water as 1, when the temperature is 37℃, the relative viscosity of whole blood is 4-5, and the relative viscosity of plasma is 1.6-2.4.

Three factors of renal injury induced by Contrast Media: Osmotic pressure, Viscosity and the total iodine. Reduced iodine intake is a feasible strategy to avoid kidney damage.

As one of the mostprofessional contrast media companies, Beiluprovides ct contrast agent, mri contrast medium, contrast media productsand etc. Want to know more? Please contact us.



在线联系供应商

至: 北京北陆药业股份有限公司
Your E-mail:
消息正文:


Send to other suppliers

Other supplier products

Calcobutrol
Calcobutrol CAS No.: Molecular formula: C18H32CaN4O9 Molecular weight: 488.5461 Quality standard: CP Characteristics: White or off-white powder ...
Traditional Chinese Medicine-Jiuweizhenxin Granules
Traditional Chinese Medicine-Jiuweizhenxin Granules As one of the best anti-anxiety drugs, Jiuweizhenxin Granulesis a modern Chinese patent medicine independently developed by Beilu Pharma for the tr...
Glimepiride Tablets
Glimepiride Tablets Glimepiride Tablets is a sulfonylurea hypoglycemic drug that can be used in combination with insulin. In 2001, Glimepiride tablets (Dibei), as the ...
Iohexol Injection
Iohexol Injection Iohexol oralis one of the different types of contrast media. Compared with a traditional ionic Contrast Media, Iohexol Injection has an excellent m...
Calcobutrol
Calcobutrol CAS No.: Molecular formula: C18H32CaN4O9 Molecular weight: 488.5461 Quality standard: CP Characteristics: White or off-white powder ...
供应产品

Same products

Chlortetracycline Premix
Chlortetracycline Premix 卖方: Hebei Shengxue Dacheng Pharmaceutical Co., Ltd. Precautions for the use of Chlortetracycline Premix in livestock feed 1. Strict compliance: &midd...
Chlortetracycline Premix
Chlortetracycline Premix 卖方: Hebei Shengxue Dacheng Pharmaceutical Co., Ltd. Chlortetracycline Premix in livestock and poultry feed: 1. Purpose: · Promote the growth o...
Chlortetracycline Premix
Chlortetracycline Premix 卖方: Hebei Shengxue Dacheng Pharmaceutical Co., Ltd. Uses of Chlortetracycline Premix ·Livestock and poultry health: Chlortetracycline Premix i...
Chlortetracycline Premix
Chlortetracycline Premix 卖方: Hebei Shengxue Dacheng Pharmaceutical Co., Ltd. Characteristics of Chlortetracycline Premix ·Natural fermentation products: Chlortetracycl...
Chlortetracycline Premix
Chlortetracycline Premix 卖方: Hebei Shengxue Dacheng Pharmaceutical Co., Ltd. Chlortetracycline Premix is a feed additive that combines chlortetracycline with premix technolog...