Contrast Media Manufacturing Company
For the purpose of medical imaging, a certain substance is introduced into the human body to change the image contrast of local tissues of the body. This introduced substance is Contrast Media, also known as Contrast Agents. Asone ofthe first contrast media manufacturing companiesin China, Beilu Pharma, as one of the most professional contrast media suppliers, contrast media companies, contrast media manufacturers, launched the domestic MRI Contrast MediumGadopentetate Dimeglumine Injection in 1992, which broke the foreign products monopoly and filled the domestic gap. As a well-known contrast media productscompany, we could provide various types of MRI contrast and a broad portfolio stems Contrast Media across CT/X-ray and MRI modalities, and own the EU standard manufacturing facilities.
Types of Contrast Media in Bei LuPharma
MRI CONTRAST MEDIA
Magnetic Resonance Imaging (MRI)Contrast Media is Gadolinium based contrast agent(GBCA). It is an intravenous injection, mainly used to enhance the image quality of internal organs, blood vessels and tissues during MRI examinations. GBCA contains gadolinium, which is connected to each other through carrier molecules to form a chelating agent. According to the different chemical structures, this contrast medium can be divided into two categories: linear and macrocyclic. The linear structure of the imaging agents is easier to release gadolinium ions, and the macrocyclic structure of the contrast material is more stable and less likely to release gadolinium ions.
CT/X-RAY CONTRAST MEDIA
Iodine-containing Contrast Media is one of the common imaging contrast agents used in radiology diagnosis and interventional therapy. It is also a basic diagnosis drug for cardiovascular imaging under X-ray. Currently, the iodinated Contrast Media used for cardiovascular system CT and digital subtraction angiography are all water-soluble organic iodinated contrast materials.
Finished Types of Contrast Media
|
Product name |
Characteristic |
Specification |
|
|
1 |
Gadopentetate Dimeglumine Injection |
Injectable solution |
469mg/ml: 10ml, 12ml, 15ml, 20ml |
|
2 |
Gadobutrol Injection |
Injectable solution |
|
|
3 |
Ammonium iron citrate |
Oral granules |
3g：0.6g（Fe 129mg） 6g：1.2g（Fe 258mg） |
|
4 |
Iopamidol Injection |
Injectable solution |
300mgI/ml: 50ml, 100ml 370mgI/ml: 50ml, 100ml |
|
5 |
Iodixanol Injection |
Injectable solution |
270mgI/ml: 100ml 320mgI/ml: 50ml, 100ml |
|
6 |
Iohexol Injection |
Injectable solution |
300mgI/ml: 20ml,50ml,75ml, 100ml 350mgI/ml: 20ml, 50ml, 100ml |
API
|
Products |
CAS NO. |
Packings |
Classification |
|
|
1 |
lohexol |
66108-95-0 |
25Kg/Drum |
API |
|
2 |
lodixanol |
92339-11-2 |
25Kg/Drum |
API |
|
3 |
lopromide |
73334-07-3 |
25Kg/Drum |
API |
|
4 |
lopamidol |
60166-93-0 |
25Kg/Drum |
API |
|
5 |
loversol |
87771-40-2 |
25Kg/Drum |
API |
|
6 |
Gadobutrol |
25Kg/Drum |
API |
|
|
7 |
Gadoterate Meglumine |
92943-93-6 |
15Kg/Drum |
API |
|
8 |
Gadopentetate Monomeglumine |
92923-57-4 |
25Kg/Drum |
API |
|
9 |
Gadopentetate Dimeglumine |
86050-77-3 |
25Kg/Drum |
API |
|
10 |
Repaglinide |
10Kg/Drum |
API |
|
|
11 |
Anhydrous Sodium Sulfate |
7757-82-6 |
25Kg/Drum |
API |
Comparison of physicochemical characteristics of commonly used Contrast Media
Contrast media
(Concentration：mg（I）/ml)
Osmotic pressure
(mOsm/kg water）
Viscosity
（cP，37℃）
Iopamidol 300
616
Ioverol 300
651
Iohexol 300
672
Iobitridol 300
695
6
Iodixanol 320
290
The osmotic pressure of normal people is about 290-300mOsm/kg.
Taking the viscosity of water as 1, when the temperature is 37℃, the relative viscosity of whole blood is 4-5, and the relative viscosity of plasma is 1.6-2.4.
Three factors of renal injury induced by Contrast Media: Osmotic pressure, Viscosity and the total iodine. Reduced iodine intake is a feasible strategy to avoid kidney damage.
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Ferric Ammonium Citrate Effervescent Granules | Ferric Ammonium Citrate Effervescent Granules was launched in 2004. It is an oral magnetic resonance contrast agent/media approved by NMPA in the m... |
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Ferric Ammonium Citrate Effervescent Granules | Ferric AmmoniumCitrate Effervescent Granules was launched in 2004. It is an oral magnetic resonance contrast agent/media approved by NMPA in the ma... |
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Iodixanol Injection | IodixanolInjection is a Contrast Media that is isotonic with plasma. It has excellent cardiac safety and renal safety, which is most comfortable to... |
