Untargeted Metabolomics
The LC-MS untargeted metabolomics is used for unbiased detection of metabolites in samples by liquid chromatography-mass spectrometry and to obtain their qualitative and quantitative information.
Technology Introduction
The main application is for comparing the case group with the control group to find the metabolites and metabolic pathways that show significant differences between groups, which can provide clues and directions for the research in biomarker development, disease pathogenesis, and drug treatment mechanisms.
Technical Features of Untargeted Metabolomics Service
Large Curated Database
Collected ultra-high sensitinity data of over 280,000 metabolites. Each sample can typically identify 1500-3000 metabolites.
Comprehensive Identification Strategy
A comprehensive identification of metabolites was performed using four qualitative methods:
Matching to in-house standard database;
Matching to integrated public database;
Matching to AI database;
Identify using the metDNA algorithm.
Rigorous Quality Control
A mature quality control system monitoring all aspects of experimentation from sample preparetion to data collection.
Applications of Untargeted Metabolomics Service
Clinical marker discovery and development
Understanding mechanisms behind disease progression
Studying drug efficacy and toxicity
Environmental toxicology research
Why Untargeted Metabolomics Service Is Used?
Genes will tell you what may happen, metabolites tell you what is happening or has happened (Bill Lasley) Metabolomics is the qualitative and quantitative assessment of metabolites (small chemical molecules<1.5 kda). The metabolites are the downstream product of protein activity as well as the result of interactions with environmental exposures, and thus they are closely related to the phenotype. Over the last decade, metabolomics is coming to the forefront as a powerful tool for understanding disease mechanisms. and identifying biomarkers, and has great potential for clinical translation.
As a professional metabolomics company, we provide untargeted metabolomics data analysis, untargeted metabolite detection, lc ms metabolomics analysis, metabolite identification lcms, untargeted metabolomics analysis, lcms metabolomicslc ms ms metabolomics, etc. For more information about what is untargeted metabolomic ands and metabolome project, please feel free to contact us!
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