Amniocentesis (BGI prenatal test)


Amniocentesis is a treatment in which amniotic liquid is eliminated from the womb for testing or treatment. Amniotic fluid is the liquid that borders as well as protects a baby during pregnancy. This liquid includes fetal cells and different healthy proteins.

Although amniocentesis can offer valuable info about your child's health and wellness, it's important to comprehend the risks of amniocentesis-- as well as be gotten ready for the results.

Why it's done

Amniocentesis can be provided for various factors:

Hereditary testing. Hereditary amniocentesis includes taking a sample of amniotic liquid and also testing it for sure conditions, such as Down syndrome.

Fetal lung testing. Fetal lung maturity screening includes taking an example of amniotic fluid and testing it to determine whether a baby's lungs are mature enough for birth.

Medical diagnosis of fetal infection. Occasionally, amniocentesis is used to review a child for infection or various other health problem. The procedure can likewise be done to review the intensity of anemia in infants that have Rh sensitization-- an unusual condition in which a mom's body immune system generates antibodies against a details healthy protein on the surface of the baby's blood cells.

Paternal screening. Amniocentesis can gather DNA from the fetus that can after that be compared to DNA from the potential papa.

Hereditary amniocentesis

Hereditary amniocentesis can provide details regarding your baby's hereditary make-up. Typically, hereditary amniocentesis is used when the examination results could have a significant influence on the management of the maternity or your wish to continue the maternity.

Hereditary amniocentesis is typically done between weeks 15 and 20 of pregnancy. Amniocentesis done before week 15 of pregnancy has been associated with a higher rate of difficulties.

You might take into consideration hereditary amniocentesis if:

You had positive arise from a prenatal screening test. If the outcomes of a screening examination-- such as the initial trimester display or prenatal cell-free DNA screening-- are positive or uneasy, you could opt for amniocentesis to confirm or eliminate a medical diagnosis.

You had a chromosomal condition or a neural tube issue in a previous pregnancy. If a previous pregnancy was affected by problems such as Down disorder or a neural tube problem-- a serious problem influencing a baby's mind or spine-- your healthcare company might recommend amniocentesis to verify or rule out these problems.

You're 35 or older. Children birthed to women 35 and also older have a greater threat of chromosomal problems, such as Down disorder. Your healthcare carrier could recommend amniocentesis to rule out these conditions.

You have a family history of a certain hereditary condition, or you or your companion is a recognized carrier of a hereditary problem. Along with recognizing Down syndrome and also the neural tube problem spina bifida, amniocentesis can be utilized to detect several various other genetic problems-- such as cystic fibrosis.

You have irregular ultrasound searchings for. Your health care company could advise amniocentesis to detect or dismiss genetic conditions related to irregular ultrasound findings.

Fetal lung maturation amniocentesis

Fetal lung maturation amniocentesis can identify whether a child's lungs await birth. This kind of amniocentesis is done only if early distribution-- either with induction or C-section-- is being considered to prevent maternity issues for the mother in a nonemergency situation. It's usually done in between 32 as well as 39 weeks of pregnancy. Earlier than 32 weeks, a baby's lungs are unlikely to be completely developed.

Amniocentesis isn't proper for everyone, nevertheless. Your healthcare service provider may prevent amniocentesis if you have an infection, such as HIV/AIDS, liver disease B or liver disease C. These infections can be transferred to your baby during amniocentesis.


Amniocentesis brings various threats, consisting of:

Dripping amniotic liquid. Seldom, amniotic liquid leakages via the vaginal area after amniocentesis. However, for the most part the amount of liquid lost is small as well as quits within one week, and also the pregnancy is likely to proceed typically.

Needle injury. Throughout amniocentesis, the infant could relocate an arm or leg into the course of the needle. Significant needle injuries are uncommon, nevertheless.

Rh sensitization. Seldom, amniocentesis might create the infant's blood cells to go into the mother's blood stream. If you have Rh adverse blood and also you have not created antibodies to Rh favorable blood, you'll be provided an injection of a blood product called Rh immune globulin after amniocentesis. This will certainly avoid your body from generating Rh antibodies that can cross the placenta and harm your infant's red cell. A blood test can detect if you've started to produce antibodies.

Infection transmission. If you have an infection-- such as hepatitis C, toxoplasmosis or HIV/AIDS -- the infection may be transferred to your baby during amniocentesis.

Keep in mind, hereditary amniocentesis is normally used when the examination results could have a considerable effect on monitoring of the maternity. Inevitably, the choice to have hereditary amniocentesis is up to you. Your health care supplier or genetic therapist can assist you weigh all the consider the decision.

How you prepare

If you're having amniocentesis done before week 20 of maternity, it could be practical to have your bladder full throughout the procedure to sustain the uterus. Drink plenty of liquids before your consultation. After 20 weeks of pregnancy, your bladder should be vacant during amniocentesis to lessen the possibility of puncture.

Your health care supplier will clarify the treatment and ask you to authorize an approval kind prior to the treatment begins. Consider asking a person to accompany you to the visit for emotional support or to drive you home afterward.

What you can expect

Amniocentesis is usually performed in an outpatient obstetric facility.

During the treatment

Initially, your health care carrier will certainly utilize ultrasound to identify the baby's precise place in your womb. You'll push your back on an examination table and expose your abdomen. Your health care service provider will use a gel to your abdomen and then utilize a little tool called an ultrasound transducer to reveal your baby's setting on a display.

Next, your healthcare supplier will clean your abdomen with an antibacterial. Normally, anesthetic isn't utilized. A lot of ladies report just light discomfort during the treatment

Assisted by ultrasound, your healthcare service provider will certainly place a thin, hollow needle via your stomach wall surface and also right into the uterus. A percentage of amniotic fluid will be withdrawn into a syringe, and the needle will be removed. The specific quantity of amniotic liquid withdrawn depends upon the variety of weeks the maternity has actually progressed.

You'll need to lie still while the needle is put and the amniotic fluid is taken out. You could observe a painful sensation when the needle enters your skin, and also you might really feel cramping when the needle enters your uterus.

After the procedure.

After amniocentesis, your healthcare carrier will certainly continue using the ultrasound to monitor your child's heart rate. You could experience cramping or moderate pelvic discomfort after an amniocentesis.

You can resume your normal activity level after the treatment. However, you may consider staying clear of arduous exercise and sexual activity for a day or 2.

At the same time, the sample of amniotic liquid will be examined in a laboratory. Some outcomes might be available within a couple of days. Other results might occupy to 4 weeks.

Call your health care service provider if you have:

Loss of or vaginal bleeding or loss of amniotic liquid via the vagina

Severe uterine cramping that lasts more than a few hrs

Inflammation and also inflammation where the needle was put.

Uncommon fetal task or a lack of fetal motion.

Your health care provider or a hereditary counselor will certainly aid you comprehend your amniocentesis outcomes.

For genetic amniocentesis, test results can accurately eliminate or detect various hereditary conditions, such as Down disorder. Nonetheless, amniocentesis can't identify all hereditary problems and also abnormality.

If amniocentesis shows that your infant has a chromosomal or genetic condition that can't be dealt with, you could deal with wrenching decisions-- such as whether to continue the pregnancy. Look for assistance from your healthcare group and also your enjoyed ones.

For fetal lung maturation amniocentesis, examination outcomes can dependably indicate a baby's lung maturity. If you require to supply the child early, this details can use confidence that your child awaits birth.

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至: Tommy Ru
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