C-Peptide

The connecting peptide, or C-peptide, is a short 31-amino-acid polypeptide that connects insulin's A-chain to its B-chain in the proinsulin molecule, releasing C-peptide and insulin from the pancreas at the same time and in about equal amounts.

So a C peptide testcan show how much insulin your body is making.

This test can be an excellent way to measure insulin levels because C-peptide tends to stay in the body longer than insulin.

A c peptide antibodytest can help tell the difference between type 1 and type 2 diabetes. With type 1 diabetes, your pancreas makes little to no insulin and little or no C-peptide. With type 2 diabetes, the body produces insulin but doesn't use it well, which can cause C-peptide levels to be higher than usual.

C-Peptide Products

Antibody	Application
Mouse Anti-human C-Peptide mAb	​ For immunodiagnostic: ELISA, LFA, CLIA

C-Peptide Intro

C-peptide (C-Peptide), also known as a connecting c peptide protein, is secreted by pancreatic beta cells, and it shares a common precursor with insulin, proinsulin. Proinsulin is split into one molecule of insulin and one molecule of C pep, so the molar amount of C-peptide and self-insulin is the same. Because the liver does not readily degrade C-peptide, C-peptide is the measurement of insulin content, accurately reflecting the function of islet cells. Blood can be drawn during the oral glucose tolerance test to measure the serum C-peptide level 1 hour, 2 hours, and 3 hours after fasting blood glucose load. The C-peptide level of ordinary people increased to more than three times the basal level after 60 minutes of glucose intake. The level of Cpeptidesin type 1 diabetes is deficient, and the postprandial C-peptide rise in patients with islet dysfunction is often less than 3-fold. For patients receiving insulin therapy, the auto-islet function cannot be evaluated by measuring insulin levels in the blood. Still, auto-islet β-cell function can assess by measuring C-peptide levels.

C-Peptide Test

C-peptide can reflect the secretory function of islet β cells in the body and has guiding significance for the classification of diabetic patients and the identification of hypoglycemia.

Determination of C-peptide levels can be applied to type diabetes and to understand the function of islet β cells in diabetic patients. Patients with type 1 or type 2 diabetes mellitus should detect the level of C-peptide or insulin to determine islet β-cell function at the beginning of the disease.

When hypoglycemia occurs in a patient suspected of having insulinoma, measuring the blood glucose to insulin ratio can help diagnose. While hypoglycemia occurs in patients treated with exogenous insulin, determination of C-peptide can identify the cause of hypoglycemia.

In addition to monitoring blood glucose, C-peptide should be measured to understand the secretory function of islet β cells after transplantation.

When suffering from hepatitis or cirrhosis, the hepatic uptake of insulin decreases, and the level of insulin in the blood tends to increase. At the same time, the C-peptide is less affected by it, and the ratio of C-peptide to insulin in the blood decreases. When nephropathy occurs, the degradation of C-peptide slows down, the level of C-peptide in blood increases, and the ratio of C-peptide to insulin is significantly higher than usual.

As a professional raw material manufacturer, Sekbiohas high-quality ivd raw materials. Welcome to contact us if needed.

Other supplier products

	Cardiac Troponin I (cTnI)	Cardiac troponin I, often denoted as cTnI, is presented in cardiac muscle tissue by a single isoform with a molecular weight of 23.9 kDa. Cardiac t...
	Thyroid Function	Thyroid Function The thyroid gland is a 2-inches long, butterfly-shaped endocrine gland generally located in the lower front of the neck. The thyr...
	Triiodothyronine (T3)	Triiodothyronine, also known as T3, is a thyroid hormone. It affects almost every physiological process in the body, including growth and developme...
	Creatine Kinase-MB (CKMB)	Creatine kinase isoenzymes are an enzyme component, among which MB type is mainly present in myocardial cells. It is also a kind ofcardiac marker. ...
	C-Reaction Protein (CRP)	C-reactive protein (CRP) refers to several proteins (acute proteins) that rise sharply in blood plasma in response to infection or tissue damage. ...

供应产品

Same products

	TPE Sealing Strip Customizable	卖方: Shijiazhuang Qimeida Rubber Material Products Co., Ltd	TPE Sealing Strip Customizable TPE sealing strips are non-toxic, environmentally friendly, pollu...
	TPE Sealing Strip Customizable	卖方: Shijiazhuang Qimeida Rubber Material Products Co., Ltd	TPE Sealing Strip Customizable TPE sealing strips are non-toxic, environmentally friendly, pollu...
	Three Types of Composite Sealing Strips	卖方: Shijiazhuang Qimeida Rubber Material Products Co., Ltd	Three Types of Composite Sealing Strips Customizable CHIMEDA three-composite sealing strip, the h...
	PU Foam Sealing Strip Customizable	卖方: Shijiazhuang Qimeida Rubber Material Products Co., Ltd	PU Foam Sealing Strip Customizable PU foamed sealing stripare made of four high-quality material...
	PVC Edge Banding Customizable	卖方: Shijiazhuang Qimeida Rubber Material Products Co., Ltd	PVC Edge Banding Customizable PVC edge bandingis made of polyvinyl chloride as the main material...