Lipopeptides

• 

A lipid molecule is added to a peptide sequence during lipidation, a peptide modification process. Since lipopeptide in skin carecan be used instead of potentially harmful adjuvants while still eliciting a thorough immune response, they are particularly interesting for vaccine development. Because synthetic peptides by themselves are insufficient to elicit an immune response, immunoadjuvants are frequently used to strengthen the reaction. In the development of peptide vaccines, alternatives to the traditional Freund's adjuvants have met with some success. These include conjugations to viral and bacterial carrier proteins, immunostimulating complexes, and branching multiple antigenic peptides (MAPS).

After Hopp and colleagues discovered in the early 1980s that a peptide conjugated to a dipalmityl-lysine moiety increased anti-hepatitis surface antigen response, lipopeptideswere initially used in vaccine development.[1] This result is explained by the fact that, despite the possibility of short peptides containing cytotoxic T cells (CTL) that bind to MHC class I molecules, they are unable to prime CD8+ T-cell responses in vivo. This was further supported by Rammensee and colleagues, who demonstrated in the early 1990s that an influenza lipopeptide (without the need for an adjuvant) evoked CTL responses but the comparable peptide without lipid conjugation did not.

Myristic acid, palmitoyl, dipalmitoyl, geranyl, farnesyl, geranylgeranyl, and other lipids are only a few of the lipids that may be linked to nearly any peptide sequence by CPC due to its significant experience and knowledge in the synthesis of peptides containing lipid moieties.

Common Lipid Abbreviations

References

Hopp, Thomas P. “Immunogenicity of a synthetic HBsAg peptide: enhancement by conjugation to a fatty acid carrier.” Molecular Immunology 21, no. 1 (1984): 13-16.

There are many peptide manufacturing companies, but we are one of the best choices for you.

Other supplier products

	Stapled Peptides	Peptides that have been "hydrocarbon stapled" are peptides that have been chemically braced with an all-hydrocarbon staple at a specified position ...
	Triptorelin Pamoate	Triptorelin pamoate for breast cancerSequence: 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-tryptophyl-L-leucyl-L-arginyl-L-prolylgl...
	Triptorelin Acetate	Triptorelin Sequence: pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2 Molecular Weight: Triptorelin AcetateProduced in: Hangzhou For mo...
	Semaglutide	Peptide semaglutideSequence: H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(C18diacid-γ-Glu-OEG-OEG)]-Glu...
	Glycosylation Peptides	A covalent alteration known as peptide glycosylationmay enhance the physicochemical characteristics of peptides. Increased bioavailability, increas...

Same products

	Dielectric Mirror	Seller: BRD Optical	A dielectric mirror, also known as a Bragg mirror, is a type of mirror composed of multiple thin ...
	T3 Horizontal Moving Walk	Seller: IFE ELEVATORS CO., LTD	IFE T3 horizontal moving walks help people move quickly and efficiently through congested areas w...
	Lipopeptides	Seller: Chinese Peptide Company	A lipid molecule is added to a peptide sequence during lipidation, a peptide modification process...
	Goserelin Acetate	Seller: Chinese Peptide Company	Molecular Weight: 1329.4762 Goserelin Acetate Produced in: Hangzhou Goserelin Acetate Application...
	Dr Rose Medical Abortion Clinic in Randburg	Seller: 125430	We provide High Quality Care in Abortion Services from 1 Week Up To 6month Using Ru486. Abortion ...