Contrast Media Manufacturing Company

For the purpose of medical imaging, a certain substance is introduced into the human body to change the image contrast of local tissues of the body. This introduced substance is Contrast Media, also known as Contrast Agents. As the first Contrast Media manufacturer in China, Beijing pharmaceuticals, as one of the most professional contrast media manufacturing companies, launched the domestic MRI Contrast Media Gadopentetate Dimeglumine Injection in 1992, which broke the foreign products monopoly and filled the domestic gap. As a well-known contrast media company, we could provide various types of MRI contrast and a broad portfolio stems Contrast Media across CT/X-ray and MRI modalities, and own the EU standard manufacturing facilities.

Types of Contrast Media in Beilu Pharma

MRI CONTRAST MEDIA

MRIContrast Mediais Gadolinium based contrast agent(GBCA). It is an intravenous injection, mainly used to enhance the image quality of internal organs, blood vessels and tissues during MRI examinations. GBCA contains gadolinium, which is connected to each other through carrier molecules to form a chelating agent. According to the different chemical structures, this contrast mediumcan be divided into two categories: linear and macrocyclic. The linear structure of the imaging agents is easier to release gadolinium ions, and the macrocyclic structure of the contrast material is more stable and less likely to release gadolinium ions.

Gadopentetate Dimeglumine Injection/API

Gadobutrol Injection/API

Gadobenate Dimeglumine Injection

Ferric Ammonium Citrate Effervescent Granules

CT/X-RAY CONTRAST MEDIA

Iodine-containing Contrast Media is one of the common imaging contrast agents used in radiology diagnosis and interventional therapy. It is also a basic diagnosis drug for cardiovascular imaging under X-ray. Currently, the iodinated Contrast Media used for cardiovascular system CT and digital subtraction angiography are all water-soluble organic iodinated contrast materials.

Iohexol Injection

Iopamidol Injection

Iodixanol Injection

Our dedication to your requirements, providing a full range of Contrast Media products

Finished Types of Contrast Media

	Product name	Characteristic	Specification
1	Gadopentetate Dimeglumine Injection	Injectable solution	469mg/ml: 10ml, 12ml, 15ml, 20ml
2	Gadobutrol Injection	Injectable solution	7.5ml
3	Ammonium iron citrate	Oral granules	3g：0.6g（Fe 129mg）
			6g：1.2g（Fe 258mg）
4	Iopamidol Injection	Injectable solution	300mgI/ml: 50ml, 100ml
			370mgI/ml: 50ml, 100ml
5	Iodixanol Injection	Injectable solution	270mgI/ml: 100ml
			320mgI/ml: 50ml, 100ml
6	Iohexol Injection	Injectable solution	300mgI/ml: 20ml,50ml,75ml, 100ml
			350mgI/ml: 20ml, 50ml, 100ml

API & Intermediates Types of Contrast Media

	Products	CAS NO.	Packings	Classification
1	Iohexol	66108-95-0	25kg	Contrast agent
2	Iodixanol	92339-11-2	25kg	Contrast agent
3	Iopromide	73334-07-3	25kg	Contrast agent
4	Iopamidol	60166-93-0	25kg	Contrast agent
5	Ioversol	87771-40-2	25kg	Contrast agent
6	Gadopentetate Monomeglumine	92923-57-4	25kg	Contrast agent
7	Gadopentetate Dimeglumine	86050-77-3	25kg	Contrast agent
8	Gadobutrol		25kg	Contrast agent
9	Calcobutrol		2kg	Excipients
10	Repaglinide		10kg	Anti-diabetic
11	Diethylenetriaminepentaacetic acid ( Pentaacetic Acid)（DTPA）	67-43-6		Intermediates
12	Iopamidol Intermediate (order based) 5-Amino-2,4,6-triiodoisophthalic acid	35453-19-1	25kg	Intermediates

Comparison of physicochemical characteristics of commonly used Contrast Media

Contrast media	Osmotic pressure	Viscosity
(Concentration：mg（I）/ml)	(mOsm/kg water）	（cP, 37℃）
Iopamidol 300	616
Ioverol 300	651
Iohexol 300	672
Iobitridol 300	695	6
Iodixanol 320	290

The osmotic pressure of normal people is about 290-300mOsm/kg.

Taking the viscosity of water as 1, when the temperature is 37℃, the relative viscosity of whole blood is 4-5, and the relative viscosity of plasma is 1.6-2.4.

Three factors of renal injury induced by Contrast Media: Osmotic pressure, Viscosity and the total iodine. Reduced iodine intake is a feasible strategy to avoid kidney damage.

Other supplier products

	Repaglinide Tablets	Repaglinide tabletsare non-sulfonylurea insulin secretion agents and are used to treat patients with type 2 diabetes. Repaglinide tablets were list...
	Contrast Media	Founded in 1992, BeijingBeiluPharmaceuticalsCompanyLimitedis mainly engaged in the research & development, production and sales of pharmaceutic...
	Ferric Ammonium Citrate Effervescent Granules	Ferric Ammonium Citrate Effervescent Granules was launched in 2004. It is an oral magnetic resonance contrast agent/media approved by NMPA in the m...
	Gadobenate Dimeglumine Injection	What's New at Beilu Beilu Pharmaceutical has been awarded BeiluPharmaceutical has been awarded "Beijing Advanced Unit of Adverse Drug Reactions D...
	Iodixanol Injection	IodixanolInjection is a CT/X-ray Contrast Media that is isotonic with plasma. It has excellent cardiac safety and renal safety, which is most comfo...

All supplier products

Same products

	Blue Non-Woven Fabric Silicone Gel Tape Roll for Scar Treatment	Seller: Zhejiang Hangbiao Medical Supplies Co., Ltd.	Surgical Tape Factory() Blue Non-Woven Fabric Silicone Gel Tape Roll is a premium scar repair pro...
	MECHANIC MEC 4K 2K HD Electronic Eyepiece Camera for Stereo Microscope	Seller: SHENZHEN PHONEFIX TECHNOLOGY CO.,LTD (CHINA PHONEFIX)	Description Mechanic MEC 2K/2K PRO/4K HD Electronic Eyepiece Camera can convert a Binocu...
	Fluke 15B+ 17B+ 18B+ Digital Multimeter Voltage Frequency Tester	Seller: PHONEFIX technology Co.,Ltd	iFixes 10CC半透明/全透明/乳白/浅黄色无铅焊膏适用于手机主板CPU BGA维修。iFixes Solder Flux注射器注射焊膏焊膏手机修整焊接耗材系列，适用于电路板纳米芯片、手机...
	Grey Rubber Stopper For Blood Collection Tube	Seller: Taizhou KangLong Medical Treatment Technology Co., Ltd.	Medical Grey Rubber Stopper For Blood Collection Tube Good formulation technology guarantees...
	HTT-02 Hot Tack Tester	Seller: Cell Instruments Co., Ltd	The HTT-02 Hot Tack Testeris specifically designed to assess this property by measuring the stren...