Contrast Media Manufacturing Company

For the purpose of medical imaging, a certain substance is introduced into the human body to change the image contrast of local tissues of the body. This introduced substance is Contrast Media, also known as Contrast Agents. As the first Contrast Media manufacturer in China, Beijing pharmaceuticals, as one of the most professional contrast media manufacturing companies, launched the domestic MRI Contrast Media Gadopentetate Dimeglumine Injection in 1992, which broke the foreign products monopoly and filled the domestic gap. As a well-known contrast media company, we could provide various types of MRI contrast and a broad portfolio stems Contrast Media across CT/X-ray and MRI modalities, and own the EU standard manufacturing facilities.

Types of Contrast Media in Beilu Pharma

MRI CONTRAST MEDIA

MRIContrast Mediais Gadolinium based contrast agent(GBCA). It is an intravenous injection, mainly used to enhance the image quality of internal organs, blood vessels and tissues during MRI examinations. GBCA contains gadolinium, which is connected to each other through carrier molecules to form a chelating agent. According to the different chemical structures, this contrast mediumcan be divided into two categories: linear and macrocyclic. The linear structure of the imaging agents is easier to release gadolinium ions, and the macrocyclic structure of the contrast material is more stable and less likely to release gadolinium ions.

Gadopentetate Dimeglumine Injection/API

Gadobutrol Injection/API

Gadobenate Dimeglumine Injection

Ferric Ammonium Citrate Effervescent Granules

CT/X-RAY CONTRAST MEDIA

Iodine-containing Contrast Media is one of the common imaging contrast agents used in radiology diagnosis and interventional therapy. It is also a basic diagnosis drug for cardiovascular imaging under X-ray. Currently, the iodinated Contrast Media used for cardiovascular system CT and digital subtraction angiography are all water-soluble organic iodinated contrast materials.

Iohexol Injection

Iopamidol Injection

Iodixanol Injection

Our dedication to your requirements, providing a full range of Contrast Media products

Finished Types of Contrast Media

	Product name	Characteristic	Specification
1	Gadopentetate Dimeglumine Injection	Injectable solution	469mg/ml: 10ml, 12ml, 15ml, 20ml
2	Gadobutrol Injection	Injectable solution	7.5ml
3	Ammonium iron citrate	Oral granules	3g：0.6g（Fe 129mg）
			6g：1.2g（Fe 258mg）
4	Iopamidol Injection	Injectable solution	300mgI/ml: 50ml, 100ml
			370mgI/ml: 50ml, 100ml
5	Iodixanol Injection	Injectable solution	270mgI/ml: 100ml
			320mgI/ml: 50ml, 100ml
6	Iohexol Injection	Injectable solution	300mgI/ml: 20ml,50ml,75ml, 100ml
			350mgI/ml: 20ml, 50ml, 100ml

API & Intermediates Types of Contrast Media

	Products	CAS NO.	Packings	Classification
1	Iohexol	66108-95-0	25kg	Contrast agent
2	Iodixanol	92339-11-2	25kg	Contrast agent
3	Iopromide	73334-07-3	25kg	Contrast agent
4	Iopamidol	60166-93-0	25kg	Contrast agent
5	Ioversol	87771-40-2	25kg	Contrast agent
6	Gadopentetate Monomeglumine	92923-57-4	25kg	Contrast agent
7	Gadopentetate Dimeglumine	86050-77-3	25kg	Contrast agent
8	Gadobutrol		25kg	Contrast agent
9	Calcobutrol		2kg	Excipients
10	Repaglinide		10kg	Anti-diabetic
11	Diethylenetriaminepentaacetic acid ( Pentaacetic Acid)（DTPA）	67-43-6		Intermediates
12	Iopamidol Intermediate (order based) 5-Amino-2,4,6-triiodoisophthalic acid	35453-19-1	25kg	Intermediates

Comparison of physicochemical characteristics of commonly used Contrast Media

Contrast media	Osmotic pressure	Viscosity
(Concentration：mg（I）/ml)	(mOsm/kg water）	（cP, 37℃）
Iopamidol 300	616
Ioverol 300	651
Iohexol 300	672
Iobitridol 300	695	6
Iodixanol 320	290

The osmotic pressure of normal people is about 290-300mOsm/kg.

Taking the viscosity of water as 1, when the temperature is 37℃, the relative viscosity of whole blood is 4-5, and the relative viscosity of plasma is 1.6-2.4.

Three factors of renal injury induced by Contrast Media: Osmotic pressure, Viscosity and the total iodine. Reduced iodine intake is a feasible strategy to avoid kidney damage.

Other supplier products

	Iohexol Injection	Iohexol Injection is a non-ionic Contrast Media. Compared with a traditional ionic Contrast Media, Iohexol Injection has an excellent molecular str...
	CT/X-Ray Contrast Media	The main component of CT/X-ray Contrast Media is iodine. The Iodinated Contrast Media is a colorless, transparent, slightly viscous liquid. At pres...
	Contrast Media Manufacturing Company	For the purpose of medical imaging, a certain substance is introduced into the human body to change the image contrast of local tissues of the body...
	Iopamidol Injection	Iopamidol Injectionis the second-generation non-ionic iodinated Contrast Media launched in the global market. In 2015, beijing pharmaceuticalsfirst...
	Gadopentetate Dimeglumine Injection/API	Since Gadopentetate Dimeglumine Injection was launched in 1992 by Beilu Pharma in China, it was highly recommended and accepted by the radiologist,...

供应产品

Same products

	Maternity and baby products of Different Brands	卖方: O&K GROUP LIMITED	Okwishing supplies all kinds of Maternity and baby products of Different Brands. Okwishing () is ...
	Medical Equipment of Different Brands	卖方: O&K GROUP LIMITED	Okwishing supplies all kinds of Medical Equipment of Different Brands. Okwishing() is a cross-b...
	MECHANIC ROBOT 6560T-B11HD 三目立体显微镜	卖方: 深圳维客修科技有限公司	描述 机械师标准版6560T-B11三目立体显微镜，放大倍数6.5-60X，45度倾斜360度旋转观察头，带WF10X25可调目镜。非常适合维修手机、平板电脑、手表等电子产品，适用于电子电路板、...
	Outdoor Sports First Aid Kit	卖方: Dongyang City Yonoel Outdoor Products Co., Ltd.	Tactical First Aid Kit, Outdoor Sports First Aid Kit, Camping Survival Bag, Medical Supplies: Fir...
	ZM-6552TH 0.65X - 5.2X 双目三目立体显微镜，适用于主板维修	卖方: 深圳维客修科技有限公司	描述 Greenough ZM-6552TH 0.65X-5.2X双目/三目立体变焦显微镜适用于手机主板/电子电路板CPU BGA焊接维修、珠宝鉴定修复、实验室观察、学术研究等。ZM-6552T...