Oligo Synthesizer
Bio-Oligo synthesizer machineis an efficient, rapid and reliable device for oligonucleotide synthesis independently developed by Jiangsu Hanbon Sci &tech co., ltd. Nowadays, the series is available to customers on two main scales: Bio-Oligo 100 laboratory nucleic automated oligonucleotide synthesismachine and Bio-Oligo Pro 400 pilot scale Bio-Oligo nucleic acid synthesizer machine. To meet different needs of customers from laboratory to pilot scale-up
Oligonucleotide From Start to Finish
We can provide oligonucleotide synthesis machinesystem to meet your needs during key areas of oligonucleotide API production, such as synthesis, purification and ultrafiltration.
In the synthesis stage, we can provide different sizes of dna oligo synthesizer to meet your needs in different stages of optimization and next step scale-up, from laboratory level to industrial production level;
In the purification stage, whether you choose reversed-phase chromatography or ion exchange methods, we have the corresponding equipment for you to choose from;
In the ultrafiltration stage, we can also provide different sizes of equipment to meet your needs for salt exchange concentration.
In a word, with Hanbon, you can find the system that matches your need for your oligonucleotide production process.
Synthesis Principle of Oligonucleotide by Synthesis Machine
Most chip oligo synthesis are currently synthesized by solid-phase synthesis, using automated equipment, in which phosphoramidite monomers are required. For example, the phosphoramidite monomer for DNA synthesis mainly consists of bases, deoxyribose, 2-cyanoethyl 5'-DMT and 3'-terminus, and diisopropylamine group, while the phosphoramidite monomer for RNA requires protection of 2'-OH to prevent cross-reaction between 2'-OH and 5'-OH in solid-phase synthesis, and the protecting group is usually TBDMS. Solid-phase synthesis is frequently used nowadays, the traditional solid-phase carriers were controlled microporous glass beads (CPG), but the loading capacity was limited, only 70-80 μmol/g. Nowadays, more high-loading capacity solid-phase carriers are used, and the loading capacity is generally up to 250umol/g~350umol/g.
For more information about oligo synthesis price and oligonucleotide synthesizer price, please feel free to contact us!
Send product request
Other supplier products
|
|
Oligo Synthesizer | Bio-Oligo synthesizer machineis an efficient, rapid and reliable device for oligonucleotide synthesis independently developed by Jiangsu Hanbon Sci... |
 |
Chromatography System | Hanbon advanced chromatography systemshas reliable performance and flexible configuration, and can provide Bio-Lab® laboratory chromatography s... |
 |
Membrane Cassette Holders | Membrane filter holderare package holders for deep filtration, ultrafiltration, and nanofiltration that range in size from 0.1 m² to 20 m²... |
 |
MCC® Manual Chromatography Column | MCC® adopts the compression way by manual screw to load packing materials, with the advantages of concise configuration , easy for cleaning and ... |
 |
Biopharm Purification Equipment | Biopharm purification equipment independently developed by Hanbon includes Chromatography columns, Chromatography system, In-line buffer dilution s... |
Same products
 |
Biopharmaceutical Equipment and Devices | Seller: Jiangsu Hanbon Science&Technology Co., LTD | Hanbon is a manufacturer of liquid ssmb chromatographyseries products with a large production sca... |
 |
SFC-Dynamic Axial Compression Column | Seller: Jiangsu Hanbon Science&Technology Co., LTD | SFC-Dynamic Axial Compression Column (DAC) has the most mature loading technology in the field of... |
 |
Preparative Liquid Chromatography System | Seller: Jiangsu Hanbon Science&Technology Co., LTD | Hanbon preparative liquid chromatography system has the characteristics of high efficiency, high ... |
 |
Preparative HPLC | Seller: Jiangsu Hanbon Science&Technology Co., LTD | Hanbon offers Hanbon preparative HPLCand MPLC from laboratory to industrial level, which are esse... |
|
|
Oligo Synthesizer | Seller: Jiangsu Hanbon Science&Technology Co., LTD | Bio-Oligo synthesizer machineis an efficient, rapid and reliable device for oligonucleotide synth... |
