Bivalirudin Trifluoroacetate
Product Name |
Bivalirudin Trifluoroacetate |
Sequence |
D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH |
Cas No. |
|
Molecular Formula |
C98H138N24O33 |
Molecular Weight |
2180.33 |
Purity (HPLC) |
98.0%min. |
Appearance |
White Powder |
Single Impurity (HPLC) |
1.0%max |
Amino Acid Composition |
±10% of theoretical |
Peptide Content (N%) |
≥80.0% |
Water Content (Karl Fischer) |
≤8.0% |
TrifluoroAcetate Content(HPIC) |
≤12.0% |
MS (ESI) |
Consistent |
Mass Balance |
95.0~105.0% |
2. Description:
Bivalirudin (Angiomax or Angiox, manufactured by The Medicines Company) is a specific and reversible direct thrombin inhibitor (DTI).
Bivalirudin is a DTI that overcomes many limitations seen with indirect thrombin inhibitors, such as heparin. Bivalirudin is a short, synthetic peptide that is potent, highly specific, and a reversible inhibitor of thrombin. It inhibits both circulating and clot-bound thrombin, while also inhibiting thrombin-mediated platelet activation and aggregation. Bivalirudin has a quick onset of action and a short half-life. It does not bind to plasma proteins (other than thrombin) or to red blood cells. Therefore it has a predictable antithrombotic response. There is no risk for Heparin Induced Thrombocytopenia/Heparin Induced Thrombosis-Thrombocytopenia Syndrome (HIT/HITTS). It does not require a binding cofactor such as antithrombin and does not activate platelets. These characteristics make bivalirudin an ideal alternative to heparin.
Bivalirudin clinical studies demonstrated consistent positive outcomes in patients with stable angina, unstable angina (UA), non-ST segment elevation myocardial infarction (NSTEMI), and ST-segment elevation myocardial infarction (STEMI) undergoing PCI in 7 major randomized trials.
Отправить запрос, связаться с поставщиком
Другие товары поставщика
Injectable Base for Bodybuilding Nandrolone Decanoate/Nandrolone Phenylpropionate | Basic Info Model NO.:434-22-0 Purity:99.29% Specific Rotation:+57.8° Ignition Residue:0.07% Trademark:Saichuang Description:White or Almo... | |
Dexamethasone-21-Acetate | Detail Dexamethasone-21-Acetate Chemical Name: Dexamethasone-17-acetate CAS: 1177-87-3 Molecular formula: C24H31FO6 MW: 434.5 Packing: ... | |
CJC-1295 Acetate | Product Name CJC-1295 Acetate Sequence Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gl... | |
Raw Material Body Building Powder Testosterone Isocaproate | Basic Info Model NO.:15262-86-9 Customized:Customized Suitable for:Adult, Testosterone Isocaproate Purity:>99% Other Name:Testosterone 17-Pr... | |
Trenbolone Ace 10161-34-9 Finaplix / Revalor-H Powder Muscle Building Bulking Steroids | Basic Info Model NO.:315-37-7 CAS No.:315-37-7 Purity:98%Testosterone Enantate Molecular Weight:400.6 Trademark:Saichuang Origin:China Syno... |
Похожие товары
10000L Bright Beer Tank | Продавец: Shandong HG Engineering Equipment Co., Ltd. | 10000L Bright Beer Tank is often also called serving tank, tax determination tanks or clear beer ... | |
2000L Fermentation Tank | Продавец: Shandong HG Engineering Equipment Co., Ltd. | 2000L Fermentation Tank is a Modular cylindrically-conical tank consist of a base tank (BT) and e... | |
300CPH(5CPM) Semi-Auto Beer Canning Machine | Продавец: Shandong HG Engineering Equipment Co., Ltd. | 300CPH(5CPM) Semi-Auto Beer Canning Machine is specifically designed to beer filling and include ... | |
2000L 2 Vessel Copper Beer Brewing Equipment | Продавец: Shandong HG Engineering Equipment Co., Ltd. | 2000L 2 Vessel Copper Beer Brewing Equipment , Copper has the highest heat conductivity, is easy ... | |
1000L 3 Vessel Beer Brewing Equipment | Продавец: Shandong HG Engineering Equipment Co., Ltd. | 1000L 3 Vessel Beer Brewing Equipment is a brewery for restaurants, commecial and industrial brew... |