Bivalirudin Trifluoroacetate
|
Product Name |
Bivalirudin Trifluoroacetate |
|
Sequence |
D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH |
|
Cas No. |
|
|
Molecular Formula |
C98H138N24O33 |
|
Molecular Weight |
2180.33 |
|
Purity (HPLC) |
98.0%min. |
|
Appearance |
White Powder |
|
Single Impurity (HPLC) |
1.0%max |
|
Amino Acid Composition |
±10% of theoretical |
|
Peptide Content (N%) |
≥80.0% |
|
Water Content (Karl Fischer) |
≤8.0% |
|
TrifluoroAcetate Content(HPIC) |
≤12.0% |
|
MS (ESI) |
Consistent |
|
Mass Balance |
95.0~105.0% |
2. Description:
Bivalirudin (Angiomax or Angiox, manufactured by The Medicines Company) is a specific and reversible direct thrombin inhibitor (DTI).
Bivalirudin is a DTI that overcomes many limitations seen with indirect thrombin inhibitors, such as heparin. Bivalirudin is a short, synthetic peptide that is potent, highly specific, and a reversible inhibitor of thrombin. It inhibits both circulating and clot-bound thrombin, while also inhibiting thrombin-mediated platelet activation and aggregation. Bivalirudin has a quick onset of action and a short half-life. It does not bind to plasma proteins (other than thrombin) or to red blood cells. Therefore it has a predictable antithrombotic response. There is no risk for Heparin Induced Thrombocytopenia/Heparin Induced Thrombosis-Thrombocytopenia Syndrome (HIT/HITTS). It does not require a binding cofactor such as antithrombin and does not activate platelets. These characteristics make bivalirudin an ideal alternative to heparin.
Bivalirudin clinical studies demonstrated consistent positive outcomes in patients with stable angina, unstable angina (UA), non-ST segment elevation myocardial infarction (NSTEMI), and ST-segment elevation myocardial infarction (STEMI) undergoing PCI in 7 major randomized trials.
Отправить запрос, связаться с поставщиком
Другие товары поставщика
 |
Raw Testosterone Undeca Powder / Test Undecanoate | Basic Info Model NO.:Test Undeca CAS No:5949-44-0 Mf:C30h48o3 Purity:98% Trademark:Saichuang Origin:China Alias:Testosterone Undeca Einecs No... |
 |
Sildenafil Mesylate | Sildenafil Mesylate CAS: Molecular Formula: C22H30B6O4S. CH3SO3H Molecular Weight: 570 Appearance: white to almost white crystalline ... |
 |
17-Methyltestosterone | 17-Methyltestosterone Synonyms: METANDREN; MESTERONE CAS: 58-18-4 MF: C20H30O2 MW: 302.45 Chemical Properties: white to slightly yellowish-white cr... |
 |
Trenbolone Hexahydrobenzyl Carbonate | Trenbolone Hexahydrobenzyl Carbonate Chemical Name: 4,9,11-estratrien-17beta-ol-3-one Hexahydrobenzyl Carbonate CAS NO.: 23454-33-3 Molecular Formu... |
 |
Nandrolone phenylpropionate | Nandrolone phenylpropionate Chemical Name: 4-estren-17beta-ol-3-one phenylpropionate CAS NO.: 62-90-8 Molecular Formula: C27H34O3 Molecular weight:... |
Похожие товары
 |
Water Bulging Bottle Making Machine | Продавец: Yongkang Hubang Machinery Technology Co., Ltd. | Yongkang Hubang Machinery Technology Co., Ltd. specializes in machinery for thermos and bottle ma... |
 |
High qiality Industry grade Microcrystalline wax for candle | Продавец: Syntop chemical Co.,Ltd. | Industrial microcrystalline wax has a wide range of applications, primarily due to its high melti... |
 |
Automatic Rainbow Lollipop Machine | Продавец: Jiangsu Flying Dragon Food Machinery Co., Ltd. | The Automatic Rainbow Lollipop Machine supports the production of colorful rainbow lollipops with... |
 |
TC SERIES 180-210 HP TRACTOR | Продавец: TIANJIN TRACTOR MANUFACTURING CO., LTD | Our company has long specialized in the development of high-horsepower wheeled tractors. This par... |
 |
TVH2704-3504（Hybrid Tractor） | Продавец: TIANJIN TRACTOR MANUFACTURING CO., LTD | Hybrid tractorsadopt a diesel engine plus motor hybrid drive system. Supported by an intelligent ... |
