Bivalirudin Trifluoroacetate
|
Product Name |
Bivalirudin Trifluoroacetate |
|
Sequence |
D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH |
|
Cas No. |
|
|
Molecular Formula |
C98H138N24O33 |
|
Molecular Weight |
2180.33 |
|
Purity (HPLC) |
98.0%min. |
|
Appearance |
White Powder |
|
Single Impurity (HPLC) |
1.0%max |
|
Amino Acid Composition |
±10% of theoretical |
|
Peptide Content (N%) |
≥80.0% |
|
Water Content (Karl Fischer) |
≤8.0% |
|
TrifluoroAcetate Content(HPIC) |
≤12.0% |
|
MS (ESI) |
Consistent |
|
Mass Balance |
95.0~105.0% |
2. Description:
Bivalirudin (Angiomax or Angiox, manufactured by The Medicines Company) is a specific and reversible direct thrombin inhibitor (DTI).
Bivalirudin is a DTI that overcomes many limitations seen with indirect thrombin inhibitors, such as heparin. Bivalirudin is a short, synthetic peptide that is potent, highly specific, and a reversible inhibitor of thrombin. It inhibits both circulating and clot-bound thrombin, while also inhibiting thrombin-mediated platelet activation and aggregation. Bivalirudin has a quick onset of action and a short half-life. It does not bind to plasma proteins (other than thrombin) or to red blood cells. Therefore it has a predictable antithrombotic response. There is no risk for Heparin Induced Thrombocytopenia/Heparin Induced Thrombosis-Thrombocytopenia Syndrome (HIT/HITTS). It does not require a binding cofactor such as antithrombin and does not activate platelets. These characteristics make bivalirudin an ideal alternative to heparin.
Bivalirudin clinical studies demonstrated consistent positive outcomes in patients with stable angina, unstable angina (UA), non-ST segment elevation myocardial infarction (NSTEMI), and ST-segment elevation myocardial infarction (STEMI) undergoing PCI in 7 major randomized trials.
Send product request
Other supplier products
 |
17-Methyltestosterone | 17-Methyltestosterone Synonyms: METANDREN; MESTERONE CAS: 58-18-4 MF: C20H30O2 MW: 302.45 Chemical Properties: white to slightly yellowish-white cr... |
 |
Finasteride | Quick Detail 1 ) Finasteride 2 ) Alias: Proscar 3 ) CAS No: 98319-26-7 4 ) MF: C23H36N2O2 5 ) MW: 372.55 6 ) Purity: 98.5% 7 ) Appearance: whi... |
 |
Heptyl Acetate | Basic Info Model NO.:112-06-1 Packaging Material:Metal CAS:112-06-1 Mf:C9h18o2 Appearance:Colorless, Slightly Floral Scent Liquid Specification... |
 |
Testosterone Propionat Test Propionat Steroids | Basic Info Model NO.:57-85-2 CAS:57-85-2 Molecular Weight:344.49 Appearance:White to Yellowish Crystalline Powder. Trademark:Saichuang Origin:C... |
 |
Primoteston Test Enanthate Testosterone Enanthate | Basic Info Model NO.:315-37-7 CAS No.:315-37-7 Purity:98%Testosterone Enantate Molecular Weight:400.6 Trademark:Saichuang Origin:China Syno... |
Same products
 |
Automotive and Motorcycle Products | Seller: Huanuo Electric Co., Ltd. | Automotive and Motorcycle Products We provide reliable automotive and motorcycle products designe... |
 |
Beeswax used for candle and handicraft production | Seller: Syntop chemical Co.,Ltd. | Advantages of Beeswax in Craft Making Stable physical properties and easy to preserve: When bees... |
 |
Beeswax used for cosmetic and candle processing | Seller: Syntop chemical Co.,Ltd. | Beeswax candles are a popular choice among natural candles, and their advantages lie primarily in... |
 |
White yellow beeswax used for cosmetic | Seller: Syntop chemical Co.,Ltd. | Usage of Beeswax Cosmetics and Personal Care: Beeswax is a natural emulsifier and thickener, com... |
 |
Common Rail Injector Valve F00R J01 329 | Seller: 828487 | Common Rail Injector Valve F00R J01 329 Common Rail Injector Valve F00R J01 522 Common ... |
