Bivalirudin Trifluoroacetate
|
Product Name |
Bivalirudin Trifluoroacetate |
|
Sequence |
D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH |
|
Cas No. |
|
|
Molecular Formula |
C98H138N24O33 |
|
Molecular Weight |
2180.33 |
|
Purity (HPLC) |
98.0%min. |
|
Appearance |
White Powder |
|
Single Impurity (HPLC) |
1.0%max |
|
Amino Acid Composition |
±10% of theoretical |
|
Peptide Content (N%) |
≥80.0% |
|
Water Content (Karl Fischer) |
≤8.0% |
|
TrifluoroAcetate Content(HPIC) |
≤12.0% |
|
MS (ESI) |
Consistent |
|
Mass Balance |
95.0~105.0% |
2. Description:
Bivalirudin (Angiomax or Angiox, manufactured by The Medicines Company) is a specific and reversible direct thrombin inhibitor (DTI).
Bivalirudin is a DTI that overcomes many limitations seen with indirect thrombin inhibitors, such as heparin. Bivalirudin is a short, synthetic peptide that is potent, highly specific, and a reversible inhibitor of thrombin. It inhibits both circulating and clot-bound thrombin, while also inhibiting thrombin-mediated platelet activation and aggregation. Bivalirudin has a quick onset of action and a short half-life. It does not bind to plasma proteins (other than thrombin) or to red blood cells. Therefore it has a predictable antithrombotic response. There is no risk for Heparin Induced Thrombocytopenia/Heparin Induced Thrombosis-Thrombocytopenia Syndrome (HIT/HITTS). It does not require a binding cofactor such as antithrombin and does not activate platelets. These characteristics make bivalirudin an ideal alternative to heparin.
Bivalirudin clinical studies demonstrated consistent positive outcomes in patients with stable angina, unstable angina (UA), non-ST segment elevation myocardial infarction (NSTEMI), and ST-segment elevation myocardial infarction (STEMI) undergoing PCI in 7 major randomized trials.
Send product request
Other supplier products
 |
Injectable Parabolan Steroid / Trenbolone Enanthate | Basic Info Model NO.:10161-33-8 Purity:99.37% Specific Rotation:+23.09° Residue on Ignition:0.05% Trademark:Saichuang Origin:China, Wuhan ... |
 |
Injectable Base for Bodybuilding Nandrolone Decanoate/Nandrolone Phenylpropionate | Basic Info Model NO.:434-22-0 Purity:99.29% Specific Rotation:+57.8° Ignition Residue:0.07% Trademark:Saichuang Description:White or Almo... |
 |
Drostanolone Enanthate Injectable Steroids | Basic Info Model NO.:Drostanolone Enanthate Customized:Non-Customized State:Solid Drostanolone Enanthate Injectable:Drostanolone Enanthate Char... |
 |
Tocopheryl Acetate Dl-Tocophrin | Basic Info Model NO.:7695-91-2 DL-TOCOPHRIN CAS:7695-91-2 Mf:C31h52o3 Appearance:White or off White Powder Specification:USP Type:Tocopheryl ... |
 |
GLP-1 (7-37) Acetate | Product Name GLP-1 (7-37) Acetate Sequence His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-... |
Same products
 |
Pipe Strap | Seller: Yuhuan Jinyi Hardware Co., Ltd. | Yuhuan JINYI Hardware Co., Ltd. offers Pipe Strap solutions designed to support and secure pipes ... |
 |
Fischer tropsch wax used for masterbatch and modified plastic | Seller: Syntop chemical Co.,Ltd. | Fischer-Tropsch wax finds extensive industrial applications, with its core values lying in its hi... |
 |
Single filter for whole blood | Seller: Guangzhou DaJi Medical Science and Technology Co., Ltd | Designedfor1 unit of whole blood (WB) volume 450ml; Computer generated filter housing with optim... |
 |
Fischer tropsch wax for epoxy resin processing | Seller: Syntop chemical Co.,Ltd. | Fischer Tropsch wax is primarily used as a lubricant and dispersant in epoxy resin processing. It... |
 |
Gr50 Pneumatic Conveying Equipment/Cast Iron Blow Through Airlock Valve | Seller: Greentech International (Zhangqiu) Co., Ltd | Rotary feeder is also called rotary pocket feeder or airlock machine.The structure of normal rota... |
