Bivalirudin Trifluoroacetate
Product Name |
Bivalirudin Trifluoroacetate |
Sequence |
D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH |
Cas No. |
|
Molecular Formula |
C98H138N24O33 |
Molecular Weight |
2180.33 |
Purity (HPLC) |
98.0%min. |
Appearance |
White Powder |
Single Impurity (HPLC) |
1.0%max |
Amino Acid Composition |
±10% of theoretical |
Peptide Content (N%) |
≥80.0% |
Water Content (Karl Fischer) |
≤8.0% |
TrifluoroAcetate Content(HPIC) |
≤12.0% |
MS (ESI) |
Consistent |
Mass Balance |
95.0~105.0% |
2. Description:
Bivalirudin (Angiomax or Angiox, manufactured by The Medicines Company) is a specific and reversible direct thrombin inhibitor (DTI).
Bivalirudin is a DTI that overcomes many limitations seen with indirect thrombin inhibitors, such as heparin. Bivalirudin is a short, synthetic peptide that is potent, highly specific, and a reversible inhibitor of thrombin. It inhibits both circulating and clot-bound thrombin, while also inhibiting thrombin-mediated platelet activation and aggregation. Bivalirudin has a quick onset of action and a short half-life. It does not bind to plasma proteins (other than thrombin) or to red blood cells. Therefore it has a predictable antithrombotic response. There is no risk for Heparin Induced Thrombocytopenia/Heparin Induced Thrombosis-Thrombocytopenia Syndrome (HIT/HITTS). It does not require a binding cofactor such as antithrombin and does not activate platelets. These characteristics make bivalirudin an ideal alternative to heparin.
Bivalirudin clinical studies demonstrated consistent positive outcomes in patients with stable angina, unstable angina (UA), non-ST segment elevation myocardial infarction (NSTEMI), and ST-segment elevation myocardial infarction (STEMI) undergoing PCI in 7 major randomized trials.
Send product request
Other supplier products
GLP-1 (7-37) Acetate | Product Name GLP-1 (7-37) Acetate Sequence His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-... | |
Anastrozole | Anastrozole Structural formula: C17H19N5 CAS NO: Molecular weight: 29337 Appearance: an off-white color crystalline powder Package: 25KG/Drum Stan... | |
Eledoisin Acetate | Product Name Eledoisin Acetate Sequence pGlu-Pro-Ser-Lys-Asp-Ala-Phe-Ile-Gly-Leu-Met-NH2 Cas No. 69-25-0 Molecular Formula ... | |
Hexarelin | Product Name Hexarelin Sequence Cas No. Molecular Formula C47H58N12O6 Molecular Weight 887.0 Appearance White P... | |
Estradiol | Quick Detail: Product Name:Estradiol;beta-estradiol-16;Estradiol;estradiolCAS:50-28-2EINECS:200-023-8Molecular Weight:272.38Molecular Formula:C18H2... |
Same products
Ukraine large diameter liquid nitrogen container KGSQ nitrogen tanks | Seller: Henan Tianzhidao Biological Technology Co., Ltd | In biological sample centers or scientific research institutions, there are a large number of cel... | |
Cambodia gas-phase liquid nitrogen tanks KGSQ liquid nitrogen container | Seller: Henan Tianzhidao Biological Technology Co., Ltd. | In biological sample centers or scientific research institutions, there are a large number of cel... | |
OY2004 | Seller: Jiaxing Ouya Machinery Manufacturing Co., Ltd. | Jiaxing Ouya Machinery Manufacturing Co., Ltd. is a manufacturer specializing in the production o... | |
Electroplated Tools | Seller: Henan E-Grind Abrasives Co., Ltd. | Henan E-Grind Abrasives Co., Ltd. produces electroplated tools by plating diamond or CBN grains w... | |
Electroplated Diamond Tools | Seller: Henan E-Grind Abrasives Co., Ltd. | Electroplated diamond drill bitscan be made in various shapes, so it will be an excellent option ... |