Bivalirudin Trifluoroacetate
|
Product Name |
Bivalirudin Trifluoroacetate |
|
Sequence |
D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH |
|
Cas No. |
|
|
Molecular Formula |
C98H138N24O33 |
|
Molecular Weight |
2180.33 |
|
Purity (HPLC) |
98.0%min. |
|
Appearance |
White Powder |
|
Single Impurity (HPLC) |
1.0%max |
|
Amino Acid Composition |
±10% of theoretical |
|
Peptide Content (N%) |
≥80.0% |
|
Water Content (Karl Fischer) |
≤8.0% |
|
TrifluoroAcetate Content(HPIC) |
≤12.0% |
|
MS (ESI) |
Consistent |
|
Mass Balance |
95.0~105.0% |
2. Description:
Bivalirudin (Angiomax or Angiox, manufactured by The Medicines Company) is a specific and reversible direct thrombin inhibitor (DTI).
Bivalirudin is a DTI that overcomes many limitations seen with indirect thrombin inhibitors, such as heparin. Bivalirudin is a short, synthetic peptide that is potent, highly specific, and a reversible inhibitor of thrombin. It inhibits both circulating and clot-bound thrombin, while also inhibiting thrombin-mediated platelet activation and aggregation. Bivalirudin has a quick onset of action and a short half-life. It does not bind to plasma proteins (other than thrombin) or to red blood cells. Therefore it has a predictable antithrombotic response. There is no risk for Heparin Induced Thrombocytopenia/Heparin Induced Thrombosis-Thrombocytopenia Syndrome (HIT/HITTS). It does not require a binding cofactor such as antithrombin and does not activate platelets. These characteristics make bivalirudin an ideal alternative to heparin.
Bivalirudin clinical studies demonstrated consistent positive outcomes in patients with stable angina, unstable angina (UA), non-ST segment elevation myocardial infarction (NSTEMI), and ST-segment elevation myocardial infarction (STEMI) undergoing PCI in 7 major randomized trials.
在线联系供应商
Other supplier products
 |
Betamethasone Dipropionate | Product Name Angiotensin Acetate Sequence H-Asp-Arg-Val-Tyr-Val-His-Pro-Phe-OH Cas No. 58-49-1 Molecular Formula C49H69N13O... |
 |
Eledoisin Acetate | Product Name Eledoisin Acetate Sequence pGlu-Pro-Ser-Lys-Asp-Ala-Phe-Ile-Gly-Leu-Met-NH2 Cas No. 69-25-0 Molecular Formula ... |
 |
Drostanolone Enanthate Injectable Steroids | Basic Info Model NO.:Drostanolone Enanthate Customized:Non-Customized State:Solid Drostanolone Enanthate Injectable:Drostanolone Enanthate Char... |
 |
Rubramin PC Powder Cyanocobalamin Vitamin B12 Vb12 with High Purity | Basic Info Model NO.:VB12 Vitamin B12:Vitamin B12 Assay:99% Molecular Weight:1355.38 . Appearance:Crystalline Welcome:Inqury Trademark:Saichuan... |
 |
Raw Testosterone Undeca Powder / Test Undecanoate | Basic Info Model NO.:Test Undeca CAS No:5949-44-0 Mf:C30h48o3 Purity:98% Trademark:Saichuang Origin:China Alias:Testosterone Undeca Einecs No... |
Same products
 |
Fischer Tropsch wax used for the processing of leather care products | 卖方: Syntop chemical Co.,Ltd. | Fischer Tropsch wax plays a significant role in the formulation of leather care products, primari... |
 |
Alloy Steel Precision Cast Construction Machinery Parts | 卖方: NingBo YinZhou ChengEn Machinery CO.,Ltd. | Application ScenariosEarthmoving Machinery: Bucket teeth, boom connectors Mining Equipment: Crus... |
 |
Fischer Tropsch Wax with high melting point for adhesive | 卖方: Syntop chemical Co.,Ltd. | Fischer Tropsch wax is an ideal additive in adhesive processing, particularly in the field of EVA... |
 |
iFixes iT23 液晶屏开启器 | 卖方: 深圳市维客修科技有限公司 | iT23液晶屏开启器，安全便捷地修复iPhone X-17系列手机及平板屏幕电脑。 |
 |
High medium low melting point Fischer Tropsch wax for candle | 卖方: Syntop chemical Co.,Ltd. | Main Applications of Fischer-Tropsch Wax in Candle Manufacturing Enhancing Gloss and Aesth... |
