Eptifibatide
|
Product Name |
Eptifibatide; |
|
Sequence |
Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2 |
|
Cas No. |
|
|
Molecular Formula |
C35H49N11O9S2 |
|
Molecular Weight |
832.4 |
|
Appearance |
White slightly yellwish powder |
|
Specific Rotation[20/D] |
-75.0～-95.0°（C=1，1%HAc） |
|
Amino Acids composition |
± 10% |
|
Peptide Purity (By HPLC) |
≥98% by area integration |
|
Related Substance (By HPLC) |
Total Impurities (%)≤2.0% Largest Single Impurity (%)≤ 1.0% |
|
Water Content (Karl Fischer) |
≤8.0% |
|
Peptide Content(N determination) |
≥80% |
|
Acetate Content |
≤15% |
|
IR spectrum |
in accordance |
Brief introduction:
Eptifibatide (Integrilin, Millennium Pharmaceuticals, also co-promoted by Schering-Plough/Essex), is an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class.[1] Eptifibatide is a cyclic heptapeptide derived from a protein found in the venom of the southeastern pygmy rattlesnake (Sistrurus miliarius barbouri).
It belongs to the class of the so-called arginin-glycin-aspartat-mimetics and reversibly binds to platelets. Eptifibatide has a short half-life. The drug is the third inhibitor of GPIIb/IIIa that has found broad acceptance after the specific antibody abciximab and the non-peptide tirofiban entered the global market.
Indications
Eptifibatide is used to reduce the risk of acute cardiac ischemic events (death and/or myocardial infarction) in patients with unstable angina or non-ST-segment-elevation (e.g., non-Q-wave) myocardial infarction (i.e., non-ST-segment elevation acute coronary syndromes) both in patients who are to receive non surgery (conservative) medical treatment and those undergoing percutaneous coronary intervention (PCI).
Отправить запрос, связаться с поставщиком
Другие товары поставщика
 |
Estradiol | Quick Detail: Product Name:Estradiol;beta-estradiol-16;Estradiol;estradiolCAS:50-28-2EINECS:200-023-8Molecular Weight:272.38Molecular Formula:C18H2... |
 |
Eptifibatide | Product Name Eptifibatide; Sequence Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2 Cas No. Molecular Formula C35H49N11O9S2 Molecular ... |
 |
CJC-1295 Acetate | Product Name CJC-1295 Acetate Sequence Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gl... |
 |
Antide Acetate | Product Name Antide Acetate Sequence Ac-D-2-Nal-p-Chloro-D-Phe-β-(3-pyridyl)-D-Ala-Ser-Lys(nicotinoyl)-D-Lys(nicotinoyl)-Leu-Lys(i... |
 |
Eledoisin Acetate | Product Name Eledoisin Acetate Sequence pGlu-Pro-Ser-Lys-Asp-Ala-Phe-Ile-Gly-Leu-Met-NH2 Cas No. 69-25-0 Molecular Formula ... |
Похожие товары
 |
Microcrystalline wax used for rubber plastic processing and modification | Продавец: Syntop chemical Co.,Ltd. | Microcrystalline wax has a wide range of industrial applications, primarily in the areas of rubbe... |
 |
Microcrystalline wax 80A used for lubrication and demolding | Продавец: Syntop chemical Co.,Ltd. | The core industrial applications of microcrystalline wax 80A are primarily focused on rubber prot... |
 |
Tyvek Flat Roll Pouch | Продавец: Hopeway AMD | Tyvek Flat Roll Pouch is designed for professional sterilization packaging, offering clean handli... |
 |
Industrial Warehouse Ceiling Fans | Продавец: Hebei Windmax Power Technology Co., Ltd. | Industrial Warehouse Ceiling Fans Industrial Warehouse Ceiling Fans for Warehouses, Logisti... |
 |
HVLS Ceiling Fan for Railway Station | Продавец: Hebei Windmax Power Technology Co., Ltd. | HVLS Ceiling Fan for Railway Station for Railway Station All units are CE-certified, manufa... |
