Eptifibatide
|
Product Name |
Eptifibatide; |
|
Sequence |
Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2 |
|
Cas No. |
|
|
Molecular Formula |
C35H49N11O9S2 |
|
Molecular Weight |
832.4 |
|
Appearance |
White slightly yellwish powder |
|
Specific Rotation[20/D] |
-75.0～-95.0°（C=1，1%HAc） |
|
Amino Acids composition |
± 10% |
|
Peptide Purity (By HPLC) |
≥98% by area integration |
|
Related Substance (By HPLC) |
Total Impurities (%)≤2.0% Largest Single Impurity (%)≤ 1.0% |
|
Water Content (Karl Fischer) |
≤8.0% |
|
Peptide Content(N determination) |
≥80% |
|
Acetate Content |
≤15% |
|
IR spectrum |
in accordance |
Brief introduction:
Eptifibatide (Integrilin, Millennium Pharmaceuticals, also co-promoted by Schering-Plough/Essex), is an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class.[1] Eptifibatide is a cyclic heptapeptide derived from a protein found in the venom of the southeastern pygmy rattlesnake (Sistrurus miliarius barbouri).
It belongs to the class of the so-called arginin-glycin-aspartat-mimetics and reversibly binds to platelets. Eptifibatide has a short half-life. The drug is the third inhibitor of GPIIb/IIIa that has found broad acceptance after the specific antibody abciximab and the non-peptide tirofiban entered the global market.
Indications
Eptifibatide is used to reduce the risk of acute cardiac ischemic events (death and/or myocardial infarction) in patients with unstable angina or non-ST-segment-elevation (e.g., non-Q-wave) myocardial infarction (i.e., non-ST-segment elevation acute coronary syndromes) both in patients who are to receive non surgery (conservative) medical treatment and those undergoing percutaneous coronary intervention (PCI).
在线联系供应商
Other supplier products
 |
Heptyl Acetate | Basic Info Model NO.:112-06-1 Packaging Material:Metal CAS:112-06-1 Mf:C9h18o2 Appearance:Colorless, Slightly Floral Scent Liquid Specification... |
 |
99% Purity Steroid Powder Testosterone Enanthate for Bodybuilding | Basic Info Model NO.:315-37-7 Customized:Customized Suitable for:Adult Purity:>99% Alias:Primoteston Depot Testosterone Enanthate CAS:315-37-... |
 |
Estradiol | Detail Quick Detail: Product Name:Estradiol;beta-estradiol-16;Estradiol;estradiolCAS:50-28-2EINECS:200-023-8Molecular Weight:272.38Mole... |
 |
Clostebol acetate | Clostebol acetate Alias: 4-chlorotestosterone acetate; 4-chloroandrost-4-ene-17beta-ol-3-one acetate CAS NO.: 855-19-6 Molecular Formula: C21H29ClO... |
 |
17-Methyltestosterone | 17-Methyltestosterone Synonyms: METANDREN; MESTERONE CAS: 58-18-4 MF: C20H30O2 MW: 302.45 Chemical Properties: white to slightly yellowish-white cr... |
