Solid Phase Peptide Synthesis

Peptide Synthesis Resins

Since Solid Phase Peptide Synthesis was first proposed by Robert Bruce Merrifield, the method of synthetic peptides became more popular than liquid phase peptide synthesis because of high efficiency. This method could assemble a peptide chain rapidly through successive reactions of amino acid derivatives on an insoluble support.

The original peptide antibiotics are also biosynthesized and extracted from the culture of polymyxa or aeruginosa. Another synthetic method of peptides is chemical synthesis, which is divided into liquid phase chemical synthesis and solid phase chemical synthesis. The liquid phase method is mainly used for the synthesis of short peptides. The solid phase synthesis method can be used to prepare long-chain peptides, cyclic peptides, and complex. Peptide. The solid phase method is divided into a Boc method and an Fmoc method. It requires the solid phase synthesis of the carrier to achieve the growth of the peptide chain by means of stepwise amino acid condensation. The advantages of solid phase synthesis are ease of purification, shortening of the synthesis cycle, and ease of automation.

Solid phase peptide synthesis(SPPS) support consists of small, polymeric resin beads functionalized with reactive group such as amine or hydroxyl groups, which link to systhesis peptide chain step by step.

Solid phase peptide synthesis(SPPS) resins is insoluble in all common solvents but swells well in most organic solvents. Better swelling degree is benefit for the reaction yields, but for short peptide easy to synthesis, lower swelling degree will be suitable and it will be good at saving solvent.

Solid phase peptide synthesisResins are rich in variety, complete in specifications and stable in performance.

Typical Applications

Solid phase synthesis of Bivalirudin

Solid phase synthesis of Eptifibatide

Solid phase synthesis of Exenatide

Solid phase synthesis of Liraglutide

Solid phase synthesis of thymopentin

Solid phase synthesis of Thymalfasin

Solid phase synthesis of Buserelin

Solid phase synthesis of Goserelin

Solid phase synthesis of Octreotide

Solid phase synthesis of Calcitonin

Our Customized Service

We also have good experiences in research and develop the amine acid pre-loading peptide resins, and we have extended resin backbone to hydrophilic matrix, such as DEG series, TEG series, PEG series. Welcome to ask for Sunresin!

Отправить запрос, связаться с поставщиком

Кому: Sunresin New Materials Co., Ltd.
Ваш E-mail:
Текст письма:

Send to other suppliers

Другие товары поставщика

Rink Amide-AM Resin
Rink Amide-AM Resin 4-(2',4'-Dimethoxyphenyl-Fmoc-aminomethyl)-phenoxyacetamido-AM resin This resin comprises the modified Rink amide linkerattached to aminomethyl res...
Size Exclusion Chromatography Media
Size Exclusion Chromatography Media Here offered is size exclusion chromatography media,including gel filtration chromatography. Category List Seplife®4BAgarose matrix, 4% content...
Weak Base Anion Exchange Resin (WBA)
Weak Base Anion Exchange Resin (WBA) SEPLITE ® Weak Base Anion Exchange Resin The Weak Base Anion Exchange Resinwith primary, secondary, tertiary amine or mixed amine group as act...
Gallium Extraction From Bayer Liquor
Gallium Extraction From Bayer Liquor Ion Exchange Sugar Refining The usual process of cane sugar is extraction, purification, evaporation, concentration, crystallization, separation, ...
Size Exclusion Chromatography Media
Size Exclusion Chromatography Media SUNRESIN IS DRIVING THE INNOVATION FOR SEPARATION TECHNIQUES Sunresin is an innovation size exclusion chromatography media , specialized in supply...
Все товары поставщика

Похожие товары

Food Plastic Boxes
Food Plastic Boxes Продавец: Yangzhou Joytoys Co., Ltd. Food packaging plastic boxes has the characteristics of long service life and high strength, and ...
OTHERS Продавец: Nantong Size Plastic Co.,Ltd As a flux for casting. Broken glass can be used as a flux for the melting of cast steel and cast...
MEDICAL & CHEMICAL Продавец: Nantong Size Plastic Co.,Ltd In our lives, the safety of medicines has attracted much attention. If the container is not safe...
HEALTH & BEAUTY Продавец: Nantong Size Plastic Co.,Ltd Glass bottles are mostly used in skin care products (creams, lotions), perfumes, essential oils, ...
THE DIFFERENCE BETWEEN PLASTIC BOTTLES AND GLASS BOTTLES FOR COSMETICS Продавец: Nantong Size Plastic Co.,Ltd Cosmetic glass bottles The glass bottle is a traditional packaging product, which is bright and ...