.

H3K9me2

As one of the professional custom peptide synthesis companiesin China, KS-V Peptide has been specialized in providing customized peptides synthesisservices(including Toxins and Analogues, Ubiquitins and Ubiquitin Probes, Post-translational Histones and other peptide manufacturing, APIs and process optimization of the pharmaceutical peptide.

SPECIFICATION OF H3K9ME2

CAT

H3105

Product Name

Histone H3-K9me2

Purity

≥95% by HPLC analysis

Appearance

White powder

Usage

Research use only

Storage

Shipping at room temperature.

Upon delivery aliquot.

Stored at -20°C or -80°C.

Avoid freeze/thaw cycle.

Sequence

ARTKQTARK(me2)S TGGKAPRKQL ATKAARKSAP ATGGVKKPHR YRPGTVALRE IRRYQKSTEL LIRKLPFQRL VREIAQDFKT DLRFQSSAVM ALQEACEAYL VGLFEDTNLC AIHAKRVTIM PKDIQLARRI RGERA

APPLICATION OF H3K9ME2

H3K9me2 is strongly associated with transcriptional repression. H3K9me2 levels are higher at silent compared to active genes in a 10kb region surrounding the transcriptional start site. H3K9me2 represses gene expression both passively, by prohibiting acetylation and therefore binding of RNA polymerase or its regulatory factors, and actively, by recruiting transcriptional repressors. H3K9me2 has also been found in megabase blocks, termed Large Organised Chromatin K9 domains (LOCKS), which are primarily located within gene-sparse regions but also encompass genic and intergenic intervals. Its synthesis is catalyzed by G9a, G9a-like protein, and PRDM2. H3K9me2 can be removed by a wide range of histone lysine demethylases (KDMs) including KDM1, KDM3, KDM4, and KDM7 family members. H3K9me2 is important for various biological processes including cell lineage commitment, the reprogramming of somatic cells to induced pluripotent stem cells, regulation of the inflammatory response, and addiction to drug use.



Отправить запрос, связаться с поставщиком

Кому: Hefei KS-V Peptide Biological Technology Co., Ltd.
Ваш E-mail:
Текст письма:


Send to other suppliers

Другие товары поставщика

SPECIFICATION OF MAMBALGIN 1
SPECIFICATION OF MAMBALGIN 1 CAT O1010-V CAS NO. Product Name Mambalgin1 Purity > 98% Form/State Lyophi...
H3K9me1
H3K9me1 As one of the professional custom peptide synthesis companiesin China, KS-V Peptide has been specialized in providing customized peptides synthesis...
PSALMOTOXIN 1
PSALMOTOXIN 1 ASIC1a channels, Psalmotoxin-1 inhibits cation currents mediated by acid-sensing ion channels (ASIC1a)1,2 SPECIFICATION OF PSALMOTOXIN 1 ...
PROTOXIN II
PROTOXIN II NaV channels and T-type Ca2+ channels, Protx-II inhibits NaV channels1. Protx-II could also modulate T-type Ca2+ channels at higher concentrations2...
SYN AKE
SYN AKE Tripeptide-3, also known as dipeptide diaminobutyryl benzyl amide diacetate or SYN®-AKE, mimics the action of wagering-1, a peptide found in ve...
Все товары поставщика

Похожие товары

Kluberoil Lamora D 220 30ml  Original Oil
Kluberoil Lamora D 220 30ml Original Oil Продавец: Guangdong Juguangheng Automation Equipment Co.,Ltd. LAMORA Doils are used for the lubrication of slideways and guideways in modern machining centres,...
LUBE SH-ONE-4S 400G for Fanuc Machines
LUBE SH-ONE-4S 400G for Fanuc Machines Продавец: Guangdong Juguangheng Automation Equipment Co.,Ltd. TheLUBE SH-ONE-4Sis a special ureagreasedesigned for appropriatelubricationmanagement of machine ...
Mobil Grease 28 Synthetic Aviation Grease
Mobil Grease 28 Synthetic Aviation Grease Продавец: Guangdong Juguangheng Automation Equipment Co.,Ltd. Mobilgrease 28resists water washing, provides superior load-carrying ability, reduces frictional ...
Kluber Isoflex Topas NCA 5051 50ml  Original Lubricants
Kluber Isoflex Topas NCA 5051 50ml Original Lubricants Продавец: Guangdong Juguangheng Automation Equipment Co.,Ltd. ISOFLEX TOPAS NCA 5051has a wide temperature range, is resistant to ageing and provides special c...
CHRISTO-LUBE MCG 111 2-OZ Valve Seal Grease
CHRISTO-LUBE MCG 111 2-OZ Valve Seal Grease Продавец: Guangdong Juguangheng Automation Equipment Co.,Ltd. Non-reactive lubricant safe for aviation oxygen equipment. Great for use on O-Rings