H3K9me2
As one of the professional custom peptide synthesis companiesin China, KS-V Peptide has been specialized in providing customized peptides synthesisservices(including Toxins and Analogues, Ubiquitins and Ubiquitin Probes, Post-translational Histones and other peptide manufacturing, APIs and process optimization of the pharmaceutical peptide.
SPECIFICATION OF H3K9ME2
|
CAT |
H3105 |
|
Product Name |
Histone H3-K9me2 |
|
Purity |
≥95% by HPLC analysis |
|
Appearance |
White powder |
|
Usage |
Research use only |
|
Storage |
Shipping at room temperature. Upon delivery aliquot. Stored at -20°C or -80°C. Avoid freeze/thaw cycle. |
|
Sequence |
ARTKQTARK(me2)S TGGKAPRKQL ATKAARKSAP ATGGVKKPHR YRPGTVALRE IRRYQKSTEL LIRKLPFQRL VREIAQDFKT DLRFQSSAVM ALQEACEAYL VGLFEDTNLC AIHAKRVTIM PKDIQLARRI RGERA |
APPLICATION OF H3K9ME2
H3K9me2 is strongly associated with transcriptional repression. H3K9me2 levels are higher at silent compared to active genes in a 10kb region surrounding the transcriptional start site. H3K9me2 represses gene expression both passively, by prohibiting acetylation and therefore binding of RNA polymerase or its regulatory factors, and actively, by recruiting transcriptional repressors. H3K9me2 has also been found in megabase blocks, termed Large Organised Chromatin K9 domains (LOCKS), which are primarily located within gene-sparse regions but also encompass genic and intergenic intervals. Its synthesis is catalyzed by G9a, G9a-like protein, and PRDM2. H3K9me2 can be removed by a wide range of histone lysine demethylases (KDMs) including KDM1, KDM3, KDM4, and KDM7 family members. H3K9me2 is important for various biological processes including cell lineage commitment, the reprogramming of somatic cells to induced pluripotent stem cells, regulation of the inflammatory response, and addiction to drug use.
Отправить запрос, связаться с поставщиком
Другие товары поставщика
 |
ACETYL OCTAPEPTIDE 3/1(SNAP-8) | Acetyl octapeptide 31(SNAP-8) Reducing the depth of wrinkles caused by contraction of facial expression muscles, especially a safer, cheaper, mild... |
 |
ACETYL TETRAPEPTIDE 5(EYESERYL) | Especially suitable for eye products, eliminating bags and dark circles, improving skin elasticity and smoothness. SPECIFICATION OF ACETYL TETRAPE... |
 |
PROTOXIN II | NaV channels and T-type Ca2+ channels, Protx-II inhibits NaV channels1. Protx-II could also modulate T-type Ca2+ channels at higher concentrations2... |
 |
OCTREOTIDE | Octreotideis a synthetic long-acting cyclic octapeptide with pharmacologic properties mimicking those of the natural hormone somatostatin. Octreoti... |
 |
H3S10PH | Synthesized histone H3 peptide corresponding to residues within 1-135 of human histone H3 with phosphorylation S10 modification. SPECIFICATION O... |
Похожие товары
 |
The Ultimate Guide to Fluorescent Dye | Продавец: Axispharm | The Ultimate Guide to Fluorescent Dye Fluorescent dyes, also known as fluorophores, are compound... |
 |
KLUBER LECTRIC KR 44-102 1KG Grease | Продавец: Guangdong Juguangheng Automation Equipment Co.,Ltd. | NSK LR380G/PC 20PC,50PC/Carton NSK AS280G/PC 20PC,50PC/Carton NSK LG280G/PC 20PC,50PC/Carton N... |
 |
KLUBER ISOFLEX TOPAS NCA52 75G Grease | Продавец: Guangdong Juguangheng Automation Equipment Co.,Ltd. | “LUBE FS-2-7 700G” LUBE FS-2-4 400G LUBE FS-2-2 200G LUBE FS-1-7 700G LUBE MY-2-7... |
 |
mbbr media | Продавец: Hangzhou NIHAO Environmental Tech Co., Ltd | As a professional OEM factory and exporter of MBBR carriers, NIHAO MBBR carriers to many large en... |
 |
Kluber ISOFLEX TOPAS L 32CN 1KG Grease for Pick and Place Machine | Продавец: Guangdong Juguangheng Automation Equipment Co.,Ltd. | NSK LR380G/PC 20PC,50PC/Carton NSK AS280G/PC 20PC,50PC/Carton NSK LG280G/PC 20PC,50PC/Carton N... |
