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Storage in Dry Form:
When stored as a dry powder, nisin is less sensitive to pH fluctuations, but exposure to moisture in alkaline environments can still trigger degradation. Thus, it is crucial to maintain a dry, acidic - neutral storage atmosphere (e.g., via desiccants in packaging).
Solution Stability:
If nisin is dissolved in a solution for storage, the pH of the solution must be carefully controlled:
Acidic Solutions (pH 3–5): Nisin solutions can remain active for longer (e.g., 24–48 hours under refrigeration).
Neutral to Alkaline Solutions (pH ≥ 7): Activity declines rapidly, making such solutions unsuitable for prolonged storage.


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