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N-Acetyl-L-Tryptophan

N-Acetyl-L-Tryptophan of Physical Properties

Form: White to off‑white crystalline powder

Odor: Odorless

Taste: Slightly bitter

Melting Point: 186-190 °C

Boiling Point: 586.6 ± 45.0 °C (at 760 mmHg, predicted)

Flash Point: 308.6 ± 28.7 °C

Decomposition: Above 200 °C, decarboxylates and releases indole derivatives.

Specific Rotation: [α]₂₀/D=+24.0° to +30.0° (c = 1, ethanol)

Chirality: Single chiral center at C‑2 (S‑configuration, L‑form)

Optical Purity: Typically ≥99% (HPLC)

Density: 1.3±0.1 g/cm³ (25 °C)

Refractive Index: n₂₀/D=1.645 (estimated)

  1. °C)

Solvent

Solubility

Water

Slightly soluble (~2.5mg/mL)

Ethanol

Soluble

Methanol

Soluble

DMSO

Freely soluble (>100mg/mL)

Acetone

Soluble

Ethyl acetate

Moderately soluble

Chloroform

Moderately soluble

Hexane

Insoluble

LogP: 0.70 (moderately lipophilic)

Polar Surface Area (PSA): 82.19 Ų

Stability: Stable under ambient conditions; incompatible with strong oxidants.

Storage: Sealed, dry, room temperature (2-8 °C recommended for long‑term).

Shelf Life: 2 years (powder, 4 °C); 3 years (−20 °C).


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