N-Acetyl-L-Tryptophan
N-Acetyl-L-Tryptophan of Physical Properties
Form: White to off‑white crystalline powder
Odor: Odorless
Taste: Slightly bitter
Melting Point: 186-190 °C
Boiling Point: 586.6 ± 45.0 °C (at 760 mmHg, predicted)
Flash Point: 308.6 ± 28.7 °C
Decomposition: Above 200 °C, decarboxylates and releases indole derivatives.
Specific Rotation: [α]₂₀/D=+24.0° to +30.0° (c = 1, ethanol)
Chirality: Single chiral center at C‑2 (S‑configuration, L‑form)
Optical Purity: Typically ≥99% (HPLC)
Density: 1.3±0.1 g/cm³ (25 °C)
Refractive Index: n₂₀/D=1.645 (estimated)
- °C)
|
Solvent |
Solubility |
|
Water |
Slightly soluble (~2.5mg/mL) |
|
Ethanol |
Soluble |
|
Methanol |
Soluble |
|
DMSO |
Freely soluble (>100mg/mL) |
|
Acetone |
Soluble |
|
Ethyl acetate |
Moderately soluble |
|
Chloroform |
Moderately soluble |
|
Hexane |
Insoluble |
LogP: 0.70 (moderately lipophilic)
Polar Surface Area (PSA): 82.19 Ų
Stability: Stable under ambient conditions; incompatible with strong oxidants.
Storage: Sealed, dry, room temperature (2-8 °C recommended for long‑term).
Shelf Life: 2 years (powder, 4 °C); 3 years (−20 °C).
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