PLTX II
SNX482
Selective, irreversible presynaptic voltage-gated Ca2+ channel blocker. Potent neurotoxin. Selective, irreversible presynaptic voltage-gated Ca2+ channel blocker. Potent neurotoxin. Selective exocytosis inhibitor. Shows insecticidal effects in vivo.
SPECIFICATION OF PLTX II
|
CAT |
C1100-V |
|
CAS NO. |
/ |
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Product Name |
PLTX-II (PLTX-II, presynaptic voltage-gated Ca2+ channel blocker) |
|
Purity |
> 98% |
|
Form/State |
Lyophilized powder |
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Solubility |
Soluble in water |
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Molecular weight |
|
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Molecular formula |
C208H313N61O70S10 |
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Source |
Synthetic peptide |
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Storage |
Shipped at room temperature. The product, as supplied, can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C. |
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Storage of solutions |
Up to two weeks at 4°C or three months at -20°C. |
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Sequence |
ADCSATGDTCDHTKKCCDDCYTCRCGTPWGANCRCDYYKARCDT (Modifications: C-terminal amide; Thr-44 = O-palmitoyl; Disulfide bonds: 3-17, 10-23, 16-35, 20-42, 25-33) |
APPLICATION OF PLTX II
PLTX II, a presynaptic calcium channel blocker in Drosophila isolated from the plectrums spider venom, is a 44-residue peptide containing ten Cys residues and an O-palmitoylated threonine amide at the carboxy-terminus
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