Factory supply Rapamycin/sirolimus 98%/Ginkgo biloba extract/Anti-biotic
ProductDescription
Rapamycin
Synonyms:23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine;Sirolimus
MolecularFormula:C51H79NO13
MolecularWeight:914.18
CAS:53123-88-9 Application:
Rapamycinisatrienemacrolideantibiotic,whichdemonstratesanti-fungal,anti-inflammatory,anti-tumorandimmunosuppressiveproperties.
RapamycinhasbeenshowntoblockT-cellactivationandproliferation,aswellas,theactivationofp70S6kinaseandexhibitsstrongbindingtoFK-506bindingproteins.Rapamycinalsoinhibitstheactivityoftheprotein,mTOR,(mammaliantargetofrapamycin)whichfunctionsinasignalingpathwaytopromotetumorgrowth.
Rapamycinbindstoareceptorprotein(FKBP12)andtherapamycin/FKB12complexthenbindstomTORandpreventsinteractionofmTORwithtargetproteinsinthissignalingpathway.
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