(R)-3-(Boc-Amino)piperidine
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CAS Number: .
Molecular Formula: C10H20N2O2.
Molecular Weight: 200.28.
Appearance: White crystalline powder.
Boiling Point: 304.8°C at 760 mmHg.
| Attribute | Details |
|---|---|
| Chemical Name | (R)-3-(Boc-Amino)piperidine |
| CAS Number | |
| Synonyms | (R)-3-Boc-Aminopiperidine; (R)-3-tert-Butoxycarbonylaminopiperidine; tert-butyl (3R)-piperidin-3-ylcarbamate; (R)-3-N-BOC-AMINO-PIPERIDINE |
| Formula | C10H20N2O2 |
| Molecular Weight | 200.28 g/mol |
| Appearance | White to off-white solid |
| Melting Point | 121.0 to 125.0 °C |
| Boiling Point | 304.8°C at 760 mmHg |
| Density | 1.02 g/cm³ |
| Solubility | Poorly soluble in water, but soluble in alcoholic organic solvents such as methanol and ethanol |
| Optical Activity | [α]22/D +3.2°, c = 0.5 in DMF |
| pKa | 12.37±0.20 (Predicted) |
| Usage | Used as an intermediate in organic synthesis and pharmaceutical chemistry, particularly for the synthesis and modification of drug molecules and biologically active molecules. It is a key intermediate in the synthesis of drugs like Linagliptin and Alogliptin, which are inhibitors of dipeptidyl peptidase-4 (DPP-4) used for lowering blood glucose levels. |
| Safety Information | Xi, N; R37/38-41-50; Keep away from heat, sparks, and open flames. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water and seek medical advice. |
| Supplier | Various companies such as E’meishan Hongsen Biomedicine Co., Ltd., Chongqing Inskay Pharmaceutical Co., Ltd., Shandong Sihuan Pharmaceutical Co., Ltd., and Anqing Qichuang Pharmaceutical Co., Ltd. |
Disclaimer: The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.
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