pharmaceutical excipient : sulfobutyl ether-beta-cyclodextrin sodium salt

Name: sulfobutyl ether-beta-cyclodextrin sodium salt DMF NO.: 030167 Other name : betadex sulfobutyl ether sodium ; sulfobutyl ether-β-cyclodextrin sodium salt CAS: Abbreviation: SBEBCD Molecular formula : C42H70-nO35 (C4H8O3S Na)n Molecular weight: 1135+158n Solubility(in 100cm3 solvent, at 25℃) : water: >50g Methanol: <0.5g Acetone : <0.5g Qaulity ： injection grade / oral grade Standard : USP38 / EP8.0 Package: 500g/bag , 1kg/bag , 2kg/bag, 10kg/drum , 20kg/drum Use : medical   ITEMS SPECIFICATION RESULTS Appearance White to off-white solid, free from foreign matter Qualify Solution Clarity A 30%w/v solution in water is clear and essentially free from particles of foreign matter Qualify Identification (IR) Consistent with SBECD standard Qualify Sodium Identification Identify test are positive for Sodium + Average Degree of Substitution 6.2-6.9 6.7 SBE 1 Content ≤0.2% 0.05% SBE 2 Content ≤0.8% 0.15% Water solution pH pH of 30%w/v solution in water is 4.0-6.8 5.4 Heavy Metals ≤5ppm <5ppm Water ≤10% 4.0% β-Cyclodextrin Content ≤0.1% Absence Sodium Chloride ≤0.2% 0.01% 1,4-butane sultone ≤0.5ppm 0.3ppm 4-Hydroxybutane-1-Sulfonic Acid ≤0.09% 0.01% Disodium bis-(4-sulfobtyl) ether ≤0.05% 0.05% Assay 95%-105% 99.5% Bacterial endotoxins ≤25EU/g ≤20EU/g Microbiology Total viable aerobic count (mould plus yeast) ≤100CFU/g 20CFU/g Escherichia Coli Absence Absence Salmonella species Absence Absence mould plus yeast ≤50CFU/g Absence Specification : USP38 Features and applications:      SBE-β-CD is a high water-soluble anionic cyclodextrin derivative. It can easily form non-covalent inclusion complexes with drug molecules, thus it has the good performances in enhancing drug stability, solubility and safety, reducing drug toxicity and hemolysis, covering up bad smell, and controlling drug release rate.         SBE-β-CD has been used in injection, oral, nasal and eye medication. Modification by charged functional units can improve the binding affinity of cyclodextrins for oppositely charged guests, so it has a special affinity for drugs with nitrogen elements.

Other supplier products

		Name: hydrxypropyl- gamma-cyclodextrin Other name : hedroxypropyl-γ-cyclodextrin Abbreviation : HPGCD CAS: Molecular formula : C48H80-nO...
		Shandong Binzhou Zhiyuan Biological Technology Co.,Ltd is one of the leading China vanillin--beta-cyclodextrin complex manufacturers and suppliers,...
		Shandong Binzhou Zhiyuan biologique Technology Co., Ltd est l'un des principaux fabricants de Chine heptakis(6-amino-6-deoxy)-bêta-cyclodextrine et...
		English name：Hydroxybutyl-beta-Cyclodextrin Other name : Hydroxybutyl-β-Cyclodextrin Abbreviation：HBBCD Standard : enterprise standard Package...
		Shandong Binzhou Zhiyuan biologique Technology Co., Ltd est l'un des principaux fabricants de mono-(6-ethanediamine-6-deoxy)-beta-cyclodextrin la C...

供应产品

Same products

	Epimedium Extract	卖方: Fruit Powder,Vegetable Powder	Product Name: Epimedium ExtractLatin Name: Epimedium Sagittatum Maxim.Specification: Icariin 5%, ...
	Pumpkin Powder	卖方: Fruit Powder,Vegetable Powder	Product Name: Pumpkin PowderLatin Name: Cucurbita pepo L.Used Part: FruitAppearance: yellow fine ...
	Broccoli Powder	卖方: Fruit Powder,Vegetable Powder	Product Name: Broccoli powder Latin Name: Brassica oleracea L.var.italic Planch. Used Part: Who...
	Pomegranate Powder	卖方: Fruit Powder,Vegetable Powder	Product Name: Pomegranate PowderLatin Name: Punica granatum linn.Used Part: Fruit juiceAppearance...
	Orange Powder	卖方: Fruit Powder,Vegetable Powder	Product Name: Orange PowderLatin Name: Citrus sinensisUsed Part: Fruit juiceAppearance: Light yel...