PROTECTIVE AGENTS (FOR LIPOSOMES)
Dehydration of liposomes（like lait liposomal）can cause the transition from liquid crystal state to gel state of phospholipids, and rehydration of dried liposomes can also be accompanied by transition from gel state to liquid crystal state, both of which can cause leakage of liposome contents, particle size increasing and the transition from single-chamber to multi-chambers. Therefore, it is very important to select a suitable lyoprotectant to reduce or eliminate the damage to liposomes caused by the lyophilization process.
Types of excipients：excipients used in formulation of liquid dosage forms ppt, excipients of semi solid dosage forms,excipients for liquid dosage form, excipients used in formulation of tablets.
TYPES OF PROTECTIVE AGENTS (FOR LIPOSOMES)
D(+)-Trehalose Dihydrate (For Injection) CAS No.: 6138-23-4
D(+)-Trehalose Dihydrate (For Injection) CAS No.: 6138-23-4
（AVT brand trehalose dihydrate (for injection) is commonly used as lyoprotectants, besides it is also stabilizer and cryoprotectant for lipid nanoparticles and mRNA.
Sucrose (For Injection) CAS No.: 57-50-1
Sucrose (For Injection) CAS No.: 57-50-1
It is injectable grade sucrose of high purity and low endotoxin, which is often used in the pharmactutical industry as a lyoprotectant in nano-formulations and protein biologics.
D(+)-Trehalose Dihydrate (For Injection) (Sterile) CAS No.: 6138-23-4
D(+)-Trehalose Dihydrate (For Injection) (Sterile) CAS No.: 6138-23-4
It is sterile trehalose dihydrate with the characteristics of high glass transition temperature, low hygroscopicity and water retention. It is also heat resistant, acid resistant and extremely stable.
HOW DO PROTECTIVE AGENTS (FOR LIPOSOMES) WORK?
How do Protective Agents (For Liposomes) Work?
The selection of freeze-drying protection agent is an important factor affecting the quality of freeze-drying. The freeze-drying process will lead to the aggregation and fusion of liposomes, accompanied by the leakage of liposome contents, while sucrose can reduce membrane fusion and protect the liposome particles from breaking and leaking drugs during the freeze-drying process. In addition, it can also act as an excipient.
AVT, a pharma excipients supplier, has been cultivating the market of high-end complex injection in China for more than ten years. AVT provides high-quality pharmaceutical excipients,such as excipients used in injections .
HAVE ANY QUESTIONS?
If you have any questions, please don't hesitate to contact us. We're always here to help with Pharmaceutical Excipients for your business. We can provide products ranging from grams to tons. AVT is able to produce and even register the product in US FDA according to your special needs.
在线联系供应商
Other supplier products
 |
D(+)-TREHALOSE DIHYDRATE (FOR INJECTION) CAS NO 6138 23 4 | Trehalose CAS NO 6138 23 4 is highly cost-effective, injection grade, product quality in line with ChP, USP, JP, EP standards, Registered in US FDA... |
 |
CHOLESTEROL (FOR LIPOSOMES) | AVT's high-purity liposome cholesterolCHO HP is obtained from lanolin after extraction, hydrogenation, and refining. The final purity can reach 99%... |
 |
CAS NO 57 50 1 SUCROSE FOR SALE (FOR INJECTION) | CAS 57 50 1 sucrose for sale is injectable grade sucrose of high purity and low endotoxin , which is often used in the pharmactutical industry as a... |
 |
BUFFER SALTS (FOR BIOLOGICAL) | Buffer salts (for Biological) belong to biological buffer systems, which contain dozens of varieties like buffered electrolyte salts,Tris and HEPES... |
 |
SUCROSE (FOR INJECTION) CAS NO.: 57-50-1 | It not only acts as a cryopreservative in the lyophilization process, but also acts as a dehydration protectant in drying and dehydration, and can ... |
Same products
 |
Methyl-3-Methoxy-2-(2-Chloromethylphenyl)-2-Propenoate | 卖方: Jostrong Tianjin Technology Co Ltd | Name:Methyl-3-Methoxy-2-(2-Chloromethylphenyl)-2-Propenoate Cas: Purity: 99% Molecular formul... |
 |
6-Ethyl-5-Fluoro-4-Hydroxy Pyrimidine | 卖方: Jostrong Tianjin Technology Co Ltd | Name: 6-Ethyl-5-Fluoro-4-Hydroxy Pyrimidine Cas: Purity: 99% Appearance: White to off-white p... |
 |
2-Hydroxy-6-(Trifluoromethyl) Pyridine | 卖方: Jostrong Tianjin Technology Co Ltd | Name: 2-Hydroxy-6-(Trifluoromethyl) Pyridine Cas: 34486-06-1 Appearance: Greyish-white powder ... |
 |
2-Methyl-4-(Trifluoromethyl) Thiazole-5-Carboxylic Acid | 卖方: Jostrong Tianjin Technology Co Ltd | Name:2-Methyl-4-(Trifluoromethyl) Thiazole-5-Carboxylic Acid Cas: Purity: 96% Appearance: Whi... |
 |
4-Chloro-6-Ethyl-5-Fluoro Pyrimidine | 卖方: Jostrong Tianjin Technology Co Ltd | Name:4-Chloro-6-Ethyl-5-Fluoro Pyrimidine Cas: Purity: 99% Appearance: Colorless to light yellow... |
