.

SPE CARTRIDGES

RayCure SPE series provides high-quality SPE cartridgesfor various types of solid phase extraction, including manifold, vacuum as well as automated solid phase extraction equipment, well compatible with RayKol automated solid-phase extraction systems. RayCure SPE cartridges utilize high-quality sorbents to ensure the efficiency of SPE clean up, offers full range of solid phase extraction cartridgefor various sample matices. Strict quality managment and control ensures high recovery rate of analytes and experiment reproducibility. RayKol provides effective, efficient and economial SPE cartridges with high performance.

SPE CARTRIDGE TYPES

RayCure SPE Column

RayCure SPE series provide pre-packed SPE columns with a variety of sorbents, resins and cartridge size for various methods and target analytes.

RULES TO SELECT RAYCURE SPE CARTRIDGE TYPES

Rule I:

The properties of solid phase packing in SPE cartridges should be match to target compounds.

Rule II:

Take the advantage of differences between analytes of interest and interferences

Rule III:

Consider nature of SPE sample matrices, characteristics of analytes and solubility of used solvents

Users can select RayCure SPE columns depending on properties of desired analytes and sample matrices as following selection guides.

Target compounds

Properties of analytes

Corresponding SPE

Solubility

Polarity/Ionicity

SPE mechanism

Sorbent phase

Water soluble

Compounds with high/low polarity

Non-polar

C18

Polymer

HLB

Ionic compounds

Anion exchange

MCX, WCX

Cation exchange

MAX, WAX

Soluble in organic solvents

Polar compounds

Normal phase bonding

PSA, NH2

Compounds with neutral polarity

Normal phase adsorption

Silica, Florisil

Non-polar compounds

Reversed phase

C18

Based on nature of SPE sample matrices

SPE sample matrices

SPE sample matrices

Target compounds

Impurities

RayCure SPE column

Fruits, vegetables, fruit juice, vegetable juice, fruit wine, herbs

Multiple pesticide residues

Carbohydrates, pigments, organic acid, phenol

RayCure QuEChERS d-SPE kits

RayCure NH2

RayCure PSA

RayCure GCB/NH2

RayCure GCB/PSA

RayCure Florisil

Weak polar pesticides

Carbohydrates, pigments, organic acid, phenol

RayCure HLB

RayCure C18

Alkali pesticides

Carbohydrates, pigments, organic acid, phenol

RayCure MCX

RayCure WCX

Acidic pesticides

Carbohydrates, pigments, organic acid, phenol

RayCure MAX

RayCure WAX

Dairy products, blood, urine, animal tissues

Neutral, weak alkali, weak acidic drugs

Proteins, fats

RayCure HLB

RayCure C18

Alkali drugs

Proteins, fats

RayCure MCX

RayCure WCX

Acidic drugs

Proteins, fats

RayCure MAX

RayCure WAX

Soil, wastewater

hydrophobic organic pollutants

Humic substances

RayCure HLB

RayCure C18

Pesticide residues

Humic substances

RayCure Florisil

Oil and grease

Fat-soluble vitamins, phospholipids, aflatoxins

Fats

RayCure Silica

RayCure NH2

RayCure PSA

HOW DOES SPE COLUMN WORK?

SPE is a conventional and efficient extraction technique, it uses the affinity of solutes dissolved or suspended in mobile phase for stationary phase to separate desired compounds from a mixture. And there are two solid phase extraction mechanisms to obtain target analytes from complex samples, to retain desired compounds in stationary phase or retain impurities in solid phase. Depending on the difference of two mechanisms, SPE procedures could be a bit various.

When sample portion passes through SPE column, undesired impurities are discarded with mobile phase, target compounds are retained in stationary phase, then rinse stationary phase with eluents to collect target compounds. It is the most commonly used purification mechanism of solid phase extraction.

In the opposite, to retain impurities in stationary phase, target compounds and few impurities are collected in mobile phase when sample portion passes through SPE column. Rinse the stationary phase which impurities is retained with solvents to obtain rest of retained target compounds. This mechanism is mostly used to eliminate fat-soluble impurities of ion analysis and analysis of multiple pesticides in fruits and vegetables.

For more information about total laboratory automation systemand automated liquid handler, please feel free to contact us!



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