H3K4ME1
Synthesized histone H3peptide corresponding to residues within 1-135 of human histone H3 with monomethylation K4 modification.
SPECIFICATION OF H3K4ME1
|
CAT |
H3101 |
|
Product Name |
Histone H3-K4me1 |
|
Purity |
≥95% by HPLC analysis |
|
Appearance |
White powder |
|
Usage |
Research use only |
|
Storage |
Shipping at room temperature. Upon delivery aliquot. Stored at -20°C or -80°C. Avoid freeze/thaw cycle. |
|
Sequence |
ARTK(me1)QTARKS TGGKAPRKQL ATKAARKSAP ATGGVKKPHR YRPGTVALRE IRRYQKSTEL LIRKLPFQRL VREIAQDFKT DLRFQSSAVM ALQEACEAYL VGLFEDTNLC AIHAKRVTIM PKDIQLARRI RGERA |
APPLICATION OF H3K4ME1
H3K4me1 enhancer is an epigenetic modification to the DNA packaging Histone H3 protein. It is a mark that indicates the mono-methylation at the 4th lysine residue of the histone H3 protein and is often associated with gene enhancers. H3K4me1 is enriched at active and primed enhancers. Transcriptional enhancers control the cell-identity gene expression and are important in cell identity. Enhancers are primed by histone H3K4 mono-/di-methyltransferase MLL4 and then are activated by histone H3K27 acetyltransferase p300. H3K4me1 fine-tunes the enhancer activity and function rather than controls. H3K4me1 is put down by KMT2C (MLL3) and KMT2D (MLL4). LSD1 and the related LSD2/KDM1B demethylate H3K4me1 and H3K4me2. Marks associated with active gene transcription like H3K4me1 and H3K9me1 have very short half-lives.H3K4me1 with MLL3/4 can also act at promoters and repress genes.
There are many peptide pharmaceutical companies, but we are one of the best choices for you.
在线联系供应商
Other supplier products
 |
KALIOTOXIN | The potent blocker of voltage-sensitive K+ channels (IC50 values are 0.1, 1.1, and 25 nM for KV1.3, KV1.1, and KV1.2 channels) respectively). Also ... |
 |
ACETYL OCTAPEPTIDE 3/1(SNAP-8) | Acetyl octapeptide 31(SNAP-8) Reducing the depth of wrinkles caused by contraction of facial expression muscles, especially a safer, cheaper, mild... |
 |
PROTOXIN II | NaV channels and T-type Ca2+ channels, Protx-II inhibits NaV channels1. Protx-II could also modulate T-type Ca2+ channels at higher concentrations2... |
 |
CALCISEPTINE | Potent, specific L-type Ca2+ channel blocker (IC50 = 15 nM). Inactive on other voltage-dependent Ca2+ channels. Smooth muscle relaxant and cardiac ... |
 |
Ω AGATOXIN IVA | P-type Ca2+ channels. ω-Agatoxin IVA is an antagonist of voltage-sensitive P-type Ca2+ channels1. It blocks neuromuscular transmission presyn... |
Same products
 |
UB AMC | 卖方: Hefei KS-V Peptide Biological Technology Co., Ltd. | UbiquitinAMCis prepared by the C-terminal derivatization of ubiquitin with 7-amino-4-methylcoumar... |
 |
SYN AKE | 卖方: Hefei KS-V Peptide Biological Technology Co., Ltd. | Tripeptide-3, also known as dipeptide diaminobutyryl benzyl amide diacetate or SYN®-AKE, mimi... |
 |
SHK TOXIN | 卖方: Hefei KS-V Peptide Biological Technology Co., Ltd. | Various KV K+ channels. Stichodactyla Toxinblocks KV1.3, KV1.1, KV1.4, and KV1.6 at subnanomolar ... |
 |
SEMAGLUTIDE AND IMPURITY | 卖方: Hefei KS-V Peptide Biological Technology Co., Ltd. | Semaglutide Peptide for Sale "Natural semaglutideis a recombinant DNA produced polypeptide ana... |
 |
PSALMOTOXIN 1 | 卖方: Hefei KS-V Peptide Biological Technology Co., Ltd. | ASIC1a channels, Psalmotoxin-1 inhibits cation currents mediated by acid-sensing ion channels (AS... |
