.

CNV-seq Detection (Semiconductor Sequencing)

CNV-seq Detection (Semiconductor Sequencing)

The detection kit, which is based on the BES 4000 platform, is used to perform low-depth whole-genome sequencing of DNA. The sequencing results are compared to the base sequence of the human reference genome, and CNVs in the tested samples are discovered using bioinformatics analysis. It is often used to find out why a woman keeps having miscarriages, find out what is wrong with an abnormal fetus, and help with a prenatal diagnosis.

What Are The Methods To Detect CNV?

There are four main methods for detecting CNVs using Next-Generation Sequencing (NGS) data: read-pair, split-read, read-depth, and assembly.

Read-Pair Method: This approach involves analyzing the distance between pairs of sequence reads. Deviations from the expected distance can indicate the presence of a CNV.

Split-Read Method: This method identifies CNVs by looking for reads that span a breakpoint. The portion of the read that aligns to the reference sequence can provide information about the CNV.

Read-Depth Method: This is the most commonly used method in NGS-based CNV detection. It works by comparing the depth of coverage in different regions of the genome. Regions with unusually high or low coverage can suggest a CNV.

Assembly Method: This approach involves assembling the reads into a new genome sequence and then comparing this sequence to the reference genome to identify CNVs.

Each of these methods has its strengths and limitations, and the choice of method often depends on the specific requirements of the study. CapitalBio Technology continues to innovate in this area, developing advanced tools and technologies to facilitate accurate and efficient CNV detection.

What Is The Principle Of CNV-Semiconductor Sequencing?

CapitalBioTechnology employs CNV-semiconductor sequencing, a specialized technique used to detect Copy Number Variations (CNVs) in the genome. CNVs are alterations of the DNA of a genome that results in the cell having an abnormal number of copies of one or more sections of the DNA.

The principle behind CNV-semiconductor sequencing involves the detection of these variations through the use of semiconductor technology. As the DNA is sequenced, the semiconductor chip detects the release of hydrogen ions, which corresponds to the incorporation of nucleotides into the DNA strand.

By comparing the sequencing data to a reference genome, CNV-semiconductor sequencing can identify regions where there are more or fewer copies of a particular DNA segment. This technique allows CapitalBio Technology to provide accurate and comprehensive genetic analysis, crucial for understanding genetic diseases and developing personalized treatments.

As one of sequencing companies, we will do our best to meet all the needs of customers.



在线联系供应商

至: CapitalBio Technology Co, Ltd.
Your E-mail:
消息正文:


Send to other suppliers

Other supplier products

CapitalBio® Microarray Hybridization Station
CapitalBio® Microarray Hybridization Station CapitalBio® Microarray Hybridization Station The CapitalBio® BioMixerTMII is a microarray hybridization station that uses continuous 3-D m...
MTB Drug Resistant Detection
MTB Drug Resistant Detection The current methods for detecting TB drug resistance are inefficient and imprecise, leading to covering drugs that either cause or exacerbate drug ...
CapitalBio® Microarray Scanner LuxScan™10K/D
CapitalBio® Microarray Scanner LuxScan™10K/D CapitalBio® Microarray Scanner Lux Scan™10K/D, a novel optical system design based on the laser confocal principle, improves detection se...
Pediatric Pharmacogenomics Detection
Pediatric Pharmacogenomics Detection The problem of drug safety for newborns and children is very serious. According to data from the Adverse Drug Reaction Monitoring Center of the Min...
Fully Integrated Platform for COVID-19
Fully Integrated Platform for COVID-19 The employment of a single system to execute all functions that are capable of being accomplished by the combination of numerous systems is an exam...
供应产品

Same products

Grey Rubber Stopper For Blood Collection Tube
Grey Rubber Stopper For Blood Collection Tube 卖方: Taizhou KangLong Medical Treatment Technology Co., Ltd. Medical Grey Rubber Stopper For Blood Collection Tube Good formulation technology guarantees...
Tactical First Aid Kit
Tactical First Aid Kit 卖方: Zhejiang Huaqi Information Technology Co., LTD This first aid kit includes a comprehensive range of supplies, from bandages and gauze to tweezer...
Camping Survival Bag
Camping Survival Bag 卖方: Zhejiang Huaqi Information Technology Co., LTD The Tactical First Aid Kit Is An Essential Companion For Outdoor Sports Enthusiasts, Campers, And...
ENHANCED VEGETAL VIGRA MALE SEX ENHANCEMENT CAPSULES
ENHANCED VEGETAL VIGRA MALE SEX ENHANCEMENT CAPSULES 卖方: GLOBAL WEIGHT LOSS LTD ENHANCED VEGETAL VIGRA ENHANCED VEGETAL VIGRA MALE SEX ENHANCEMENT CAPSULES ENHANCED VEGETAL VIGR...
ORGANIC HONEY CANDY POWER
ORGANIC HONEY CANDY POWER 卖方: GLOBAL WEIGHT LOSS LTD Organic Power Honey Candy for Men- Pack of 6 Candies ORGANIC POWER CANDY ORGANIC CANDY HONEY ORGA...