4-Methylcinnamic Acid
English name : 4-Methylcinnamic Acid
Other names : 4-Methylcinnamic aldehyde; (2E)-3-(4-Methylphenyl)-2-propenoic acid;2-Propenoic acid, 3-(4-methylphenyl)-; Cinnamic acid, p-methyl-; AKOS BBS-00007857;AKOS BBB/231; METHYLCINNAMIC ACID,4-TRANS; 4-METHYLCINNAMIC ACID
CAS No. : 1866-39-3
Molecular formula : C10H10O2Molecular weight : 161.178
Molar mass : 161.178 g/molMelting point : 198-201°C
Boiling point : 228.88°C (rough estimate)
Flash point :206.1°C
Refractive index :1.5766Properties : White Crystalline Powder
Purity : 99%
Packaging : 25kg
Storage method : Store below 30°CUsage :
It is used to synthesize methyl p-methyl cinnamate. Methyl p-methyl cinnamate is mainly used to synthesize p-bromomethyl cinnamate as the upstream raw material of the antithrombotic drug Ozagrel sodium. P-bromomethylcinnamate is brominated with N-bromosuccinimide to produce p-bromomethylcinnamate. Methyl p-bromomethylcinnamate is in ionic liquid N-n-butylpyridine tetrafluoroborate. After condensing with imidazole at room temperature in the acid salt, alkaline hydrolysis was performed to obtain the antithrombotic drug ozagrel sodium, with a total yield of 67%.
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