4-methyl cinnamic acid methyl ester
Name: 4-methyl cinnamic acid methyl ester
CAS No.: 20754-20-5
Formula: C11H12O2
Molecular Weight: 176.21
Melting point: 58～62℃
Boiling point: 273℃
Density:1.057g/cm3
Flash point:152℃
Refractive index:（20°C）1.5371
Molar volume:（m3/mol）153.3
Appearance:Color white to pale yellow crystalline powder
Purity:>98%
Packagespecification:25 kg / cardboard drum
Storage:Pay attention to the source of fire, especially to avoidsunlight, and store in a cool place.
Usage:
METHYL4-METHYLCINNAMATE is mainly used to synthesize methyl p-bromomethyl cinnamate as an upstream raw material for the antithrombotic drug Ozagrel Sodium. P-bromomethylcinnamate is brominated with N-bromosuccinimide to produce p-bromomethylcinnamate. Methyl p-bromomethylcinnamate is in ionic liquid N-n-butylpyridine tetrafluoroborate. After alkaline condensation with the imidazole in the acid salt at room temperature, the antithrombotic drug ozagrel sodium was obtained with a total yield of 67%。
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