4-methyl cinnamic acid methyl ester

Name: 4-methyl cinnamic acid methyl ester

CAS No.: 20754-20-5

Formula: C11H12O2

Molecular Weight: 176.21

Melting point: 58~62℃

Boiling point: 273℃


Flash point:152℃

Refractive index:(20°C)1.5371

Molar volume:(m3/mol)153.3

Appearance:Color white to pale yellow crystalline powder


Packagespecification:25 kg / cardboard drum

Storage:Pay attention to the source of fire, especially to avoidsunlight, and store in a cool place.


METHYL4-METHYLCINNAMATE is mainly used to synthesize methyl p-bromomethyl cinnamate as an upstream raw material for the antithrombotic drug Ozagrel Sodium. P-bromomethylcinnamate is brominated with N-bromosuccinimide to produce p-bromomethylcinnamate. Methyl p-bromomethylcinnamate is in ionic liquid N-n-butylpyridine tetrafluoroborate. After alkaline condensation with the imidazole in the acid salt at room temperature, the antithrombotic drug ozagrel sodium was obtained with a total yield of 67%。


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