Trans-4-[(tert-butoxycarbonyl)amino] cyclohexanecarboxylic acid
1. Basic Information
Product Name: Trans-4-[(tert-butoxycarbonyl)amino] cyclohexanecarboxylic acid
CAS Number: 53292-89-0
Aliases: Cis-4-(tert-Butoxycarbonylamino) cyclohexanecarboxylic acid, trans-4-(tert-Butoxycarbamoylamino)
cyclohexanecarboxylic acid, TRANS-4-(N-BOC-amino) cyclohexanecarboxylic acid, BOC-trans-4-amino
cyclohexanecarboxylic acid, etc.
Purity: High purity product up to 99%
Molecular Formula: Specific molecular formula should refer to specialized chemical databases or related
literature
Origin: Hubei Province, China, among other locations
2. Physical Properties
Appearance: White crystalline powder
Melting Point: 181.0–185.0°C (The exact melting point may vary slightly depending on product purity,
preparation methods, etc.)
Odor: No specific odor
Solubility: Specific solubility data should refer to relevant literature or experimental data
3. Chemical Properties
Trans-4-[(tert-butoxycarbonyl)amino] cyclohexanecarboxylic acid is a cyclohexanecarboxylic acid derivative
with an amino group protected by a BOC (tert-butoxycarbonyl) group. It exhibits specific chemical
properties and can undergo chemical reactions such as esterification, amidation, etc., to form
corresponding derivatives under certain conditions.
4. Applications
·Pharmaceutical Industry: It is an important pharmaceutical intermediate used in the synthesis of
dipeptides, tripeptides, quinine analogs, and other pharmaceutical compounds.
·Other Industries: It also has broad application prospects in food, pesticide, and daily chemical industries.
5. Preparation and Synthesis
Trans-4-[(tert-butoxycarbonyl)amino] cyclohexanecarboxylic acid can be synthesized by reacting
cyclohexanecarboxylic acid with di-tert-butyl dicarbonate under specific reaction conditions. The detailed
preparation methods and conditions should refer to relevant literature or professional texts.
6. Safety and Environmental Protection
When using Trans-4-[(tert-butoxycarbonyl)amino] cyclohexanecarboxylic acid, it is important to follow
relevant safety operating procedures and environmental protection requirements.
Avoid direct contact with skin, eyes, etc. In case of accidental contact, rinse immediately with plenty of
water and seek medical attention.
During storage, keep the container tightly closed and store it in a dry, ventilated place, avoiding direct
sunlight and high temperatures.
Trans-4-[(tert-butoxycarbonyl)amino] cyclohexanecarboxylic acid is an important intermediate in fine
chemicals with broad applications in pharmaceuticals, food, pesticides, and other fields. Safety operating
procedures and environmental protection requirements should be followed during use and storage.
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