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Nisin

Due to nisin's antibacterial activity against drug-resistant gram-positive bacteria (e.g., methicillin-resistant Staphylococcus aureus, MRSA), nisin is being researched for non-oral medical applications (it is broken down by gut enzymes, so oral use for systemic infections is limited):
Topical formulations: Developed into creams, ointments, or wound dressings to treat skin infections caused by gram-positive bacteria (e.g., MRSA-induced skin ulcers or burns). It is also tested in oral care products (e.g., mouthwashes, toothpaste) to inhibit Streptococcus mutans (the main bacterium causing tooth decay).
Medical device coatings: Coated on catheters, implants (e.g., orthopedic implants), or surgical instruments to prevent bacterial adhesion and biofilm formation (a major cause of hospital-acquired infections like catheter-related bloodstream infections).


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Key Application Precautions of Nisin
Key Application Precautions of Nisin Key Application Precautions of Nisin Antibacterial Spectrum Limitation: Nisin is ineffective against Gram-negative bacteria (e.g., E. coli) and mol...
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Nisin in Food Preservation Core Advantages of Nisin in Food Preservation Natural and Safe: Produced by lactic acid bacteria, non-toxic, and exempt from ADI (Acceptable Daily ...
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Regulatory Standards and Dosage Limits of Nisin Global regulatory agencies have established strict usage standards for Nisin:FAO/WHO: The acceptable daily intake (ADI) is set at 0–3300 IU/k...
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