H3K4me1
As one of the professional custom peptide synthesis companiesin China, KS-V Peptide has been specialized in providing customized peptides synthesisservices(including Toxins and Analogues, Ubiquitins and Ubiquitin Probes, Post-translational Histones and other peptide manufacturing, APIs and process optimization of the pharmaceutical peptide.
SPECIFICATION OF H3K4ME1
|
CAT |
H3101 |
|
Product Name |
Histone H3-K4me1 |
|
Purity |
≥95% by HPLC analysis |
|
Appearance |
White powder |
|
Usage |
Research use only |
|
Storage |
Shipping at room temperature. Upon delivery aliquot. Stored at -20°C or -80°C. Avoid freeze/thaw cycle. |
|
Sequence |
ARTK(me1)QTARKS TGGKAPRKQL ATKAARKSAP ATGGVKKPHR YRPGTVALRE IRRYQKSTEL LIRKLPFQRL VREIAQDFKT DLRFQSSAVM ALQEACEAYL VGLFEDTNLC AIHAKRVTIM PKDIQLARRI RGERA |
APPLICATION OF H3K4ME1
H3K4me1 enhanceris an epigenetic modification to the DNA packagingHistone H3 protein. It is a mark that indicates the mono-methylation at the 4th lysine residue of the histone H3 protein and is often associated with gene enhancers. H3K4me1 is enriched at active and primed enhancers. Transcriptional enhancers control the cell-identity gene expression and are important in cell identity. Enhancers are primed by histone H3K4 mono-/di-methyltransferase MLL4 and then are activated by histone H3K27 acetyltransferase p300. H3K4me1 fine-tunes the enhancer activity and function rather than controls. H3K4me1 is put down by KMT2C (MLL3) and KMT2D (MLL4). LSD1 and the related LSD2/KDM1B demethylate H3K4me1 andH3K4me2. Marks associated with active gene transcription like H3K4me1 andH3K9me1have very short half-lives.H3K4me1 with MLL3/4 can also act at promoters and repress genes.
Отправить запрос, связаться с поставщиком
Другие товары поставщика
 |
H3S10PH | Synthesized histone H3 peptide corresponding to residues within 1-135 of human histone H3 with phosphorylation S10 modification. SPECIFICATION O... |
 |
ACETYL OCTAPEPTIDE 3/1(SNAP-8) | Acetyl octapeptide 31(SNAP-8) Reducing the depth of wrinkles caused by contraction of facial expression muscles, especially a safer, cheaper, mild... |
 |
PALMITOYL PENTAPEPTIDE 4 | Palmitoyl pentapeptide-4 (Matrixyl®) is a small, highly specific bioactive peptide that is reported to stimulate the production of elastin, fib... |
 |
H3K9me2 | As one of the professional custom peptide synthesis companiesin China, KS-V Peptide has been specialized in providing customized peptides synthesis... |
 |
H3K36me3 | As one of the professional custom peptide synthesis companiesin China, KS-V Peptide has been specialized in providing customized peptides synthesis... |
Похожие товары
 |
Sucralose Purchase price | Продавец: Shanghai Yifu Food Ingredients Co., Ltd | Sucralose, as a high-sweetness, calorie-free, and highly stable artificial sweetener, enjoys wide... |
 |
Sucralose Partners, long-termCooperation | Продавец: Shanghai Yifu Food Ingredients Co., Ltd | Sucralose is currently a widely used high-potency sweetener globally. Its safety has been verifie... |
 |
Sucralose | Продавец: Shanghai Yifu Food Ingredients Co., Ltd | Sucralose is a high-sweetness agent obtained by replacing the hydroxyl groups at positions 4, 1',... |
 |
Sucralose | Продавец: Shanghai Yifu Food Ingredients Co., Ltd | Sucralose is a trichloro derivative of sucrose (4,1',6'-trichloro-4,1',6'-dideoxy-galactosucrose)... |
 |
Sucralose | Продавец: Shanghai Yifu Food Ingredients Co., Ltd | Thermal properties of SucraloseMelting point / Decomposition point: Approximately 125°C (deco... |
