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Nisin

Safety
·Non-toxic and Safe: Nisin is a safe, non-toxic, and highly effective natural preservative. Once ingested, it is easily broken down by plant proteases, does not affect the normal gut microbiota, and does not contribute to antibiotic resistance or cross-resistance with other antibiotics.
·Safety Certification: Nisin's safety has been widely recognized. In 1969, the Joint Expert Committee on Food Additives of the FAO/WHO (Food and Agriculture Organization/World Health Organization) confirmed that nisin is safe for use as a food preservative.


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Toxicological Safety of Nisin Acute and Chronic Toxicity: Acute toxicity studies show that Nisin has an LD₅₀ > 5000 mg/kg in rodents (oral administration), indicating extreme...
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